Manager of Genomics Core

Position Overview

The Genome Sciences Core at Penn State University College of Medicine in Hershey, PA is seeking a highly skilled and collaborative Manager to lead operations of a state-of-the-art genomics facility. This role is responsible for overseeing daily core functions, supporting cutting‑edge genomics and multi‑omics research, and partnering with investigators to deliver high‑quality, reliable data. The Manager will provide technical and operational leadership, ensure service excellence, and contribute to the strategic growth and sustainability of the core.

• Oversee daily operations of the Genome Sciences Core, including workflow management, quality control, and service delivery timelines.
• Lead and support genomics services such as next‑generation sequencing (NGS), single‑cell sequencing, and other emerging multi‑omic technologies.
• Collaborate with investigators on experimental design, project planning, and execution to ensure high‑quality outcomes.
• Supervise, train, and mentor core staff; foster a collaborative and high‑performing team environment.
• Manage budgets, pricing, and cost‑recovery models to ensure financial sustainability.
• Evaluate, implement, and optimize new technologies and platforms to maintain a cutting‑edge facility.
• Support grant applications and institutional research initiatives by providing technical expertise and resource planning.
• Ensure compliance with institutional policies, data management standards, and best practices.

• Significant hands‑on experience with genomics technologies (e.g., NGS platforms, library preparation, sequencing workflows).
• Demonstrated experience in laboratory or core facility operations.
• Strong organizational, project management, and problem‑solving skills.
• Excellent communication and interpersonal skills.

• PhD degree in a relevant field.
• Experience managing a core facility, shared resource lab, or technical team.
• Familiarity with single‑cell, spatial genomics, or other advanced multi‑omic approaches.
• Experience with budgeting, service pricing, and cost‑recovery models.
• Knowledge of data analysis workflows or collaboration with bioinformatics teams.

This position plays a critical role in supporting innovative research across Penn State by providing access to advanced genomic technologies and expertise. The successful candidate will help drive scientific impact while contributing to the growth and long‑term sustainability of the core.

For Research Project Manager – Intermediate Professional:
Master’s Degree, 1+ years of relevant experience, or equivalent combination of education and experience; no required certifications.

For Research Project Manager – Advanced Professional:
Master’s Degree, 3+ years of relevant experience, or equivalent combination of education and experience; no required certifications.

Employment requires successful completion of background checks in accordance with University policies. Applicants must be authorized to work in the U.S.;
Penn State does not sponsor visa status.

Salary range: $61,800.00 – $.

Benefits include comprehensive medical, dental, and vision coverage; robust retirement plans; paid time off (holidays, vacation, sick time); and a generous 75% tuition discount for employees and eligible dependents.

Penn State is an equal‑opportunity employer and is committed to providing employment opportunities to all qualified applicants without regard to race, color, religion, age, sex, sexual orientation, gender identity, national origin, disability, or protected veteran status. If you are unable to use our online application process due to an impairment or disability, please contact 814‑865‑1473.

Penn State is committed to advancing equity, respect, and belonging, fostering a culture that supports inclusion and provides opportunities for engagement across the community.