Senior Scientist II, Biophysics

Senior Scientist II, Biophysics (Drug Discovery) Hoddesdon

Pharmaron is a global CRO helping pharma and biotech companies bring new therapies to life. With over 21,000 employees worldwide across 23 sites across the UK, US and China, and we support drug discovery through to manufacturing with fully integrated, high-quality services.

We're proud of the impact we make—just last year, we supported over 780 discovery projects
, 1,000+ CMC programmes
, and 1,000+ clinical trials across all phases. Our teams are involved in everything from small molecules to gene therapies, and we work with more than 3,000 global customers
.

We are seeking a highly skilled Biophysical Chemist with proven expertise in Surface Plasmon Resonance (SPR) and assay development to join our team. In this role, you will play a pivotal part in advancing drug discovery projects by designing, developing, and validating assays, interpreting complex data, and overcoming assay-related challenges with creativity and precision. You will thrive in a collaborative environment, working closely with colleagues to drive innovation, while also demonstrating the independence and initiative needed to deliver results.

This is an exciting opportunity for a scientist who combines technical excellence with problem-solving skills and a passion for discovery. If you are ready to make a meaningful impact and contribute to groundbreaking research, we would love to hear from you.

Please note: Unfortunately, we are unable to offer visa sponsorship for this position, now or in the future. Candidates must have the right to work in the UK at the time of application.

At Pharmaron we offer:

• Vibrant and dynamic employment - we are a highly specialised, growth company operating in a critical sector of the economy - our future is strong and exciting!
• Opportunities to develop your skills and yourself - our rapid growth brings greater opportunities for you to learn and grow faster!
• A great team where we all support each other - enjoy your work - after all you spend about a third of your time here!

• To support biology projects by working independently to plan, execute and deliver on project goals.
• Demonstrate competency in the core laboratory skills required to support biology assay development, validation and screening. Such skills include, but are not limited to, routine use of core instrumentation and laboratory techniques, guided use of higher end laboratory techniques and instrumentation, and an understanding how their work influences drug discovery.
• Execute experiments, interpret results, and be able to plan and recommend next steps and/or additional experiments in a timely manner to solve scientific issues. Where appropriate the individual will seek guidance (from a scientific supervisor / Line Manager) due to the level of complexity and/or the requirement for strategic input.
• Communicate with cross-functional teams to ensure that scientific work is appropriately reported via laboratory notebooks and presentations both internally and externally to the client.
• Document and report results of all experiments in a manner consistent with department practices and governing procedures, as applicable

• Ph.D. in Biochemistry, Biophysics or a related field, with at least three years of relevant work experience, or a M.S. with five years of relevant work experience
• Experience of using Surface Plasmon Resonance (SPR) is required
• Experience using biophysical techniques used to analyse protein-protein interactions and protein-small molecule interactions.
• Practical experience with biophysical techniques such Microscale Thermophoresis (MST), Isothermal Titration Calorimetry (ITC), Differential Scanning Fluorimetry (DSF) is required.
• Candidates with experience running FP, FRET, kinetic FRET assays or Mass Spectroscopy with relevant knowledge in Drug Discovery field will also be considered
• Expertise with the kinetic and thermodynamic characterization of ligand binding as well as quantitative data management and analysis
• Excellent communication skills and ability to present rationale, key data, issues and accomplishments to other members of the…