Senior Director, Platform & Process Development

Overview

Position:
Senior Director, Platform & Process Development

Oligo Factory delivers high-quality custom DNA and RNA oligos at scale to pharmaceutical, diagnostics and life science customers with a focus on customer responsiveness and satisfaction. In 2023, Oligo Factory’s Holliston, MA facility achieved ISO 13485:2016 certification and ICH Q7 compliance, marking a milestone in our dedication to quality systems that support customer oligonucleotide demands. We continue to invest in technology and people to serve the growing demands of scientific discoveries.

Our third-generation synthesis platform (NANDA Series) enhances turn-around-time, control and quality. Oligo Factory products and services are built to serve all the DNA/RNA synthesis markets and applications, from synthetic biology to qPCR to functional genomics and therapeutics.

Location:

Holliston, MA, USA (on-site)
• Number of Employees: 15+
•

Reports to:

CEO
• Direct Reports: 1 (Scientist II, Platform & Process Development)
• Key Interfaces:
Commercial, Manufacturing Operations, Quality & Facilities

• Owning and leading the technical development strategy including leading scientific/co-development collaborations.
• Leading the development & optimization of platform programs aligned to target product profiles.
• Scaling process development and leading tech transfer to Manufacturing Operations.
• Driving process scalability, standardization, and operational efficiency.
• Assessing & evaluating new synthesis and purification technologies.
• Leading troubleshooting and root-cause investigations for complex technical challenges.

• M.S. in Chemistry, Biochemistry, Chemical Engineering, or Molecular Biology;
  Ph.D. preferred.
• 8-12 years of experience in oligonucleotide synthesis and process development; experience with high-throughput or parallel oligonucleotide synthesis strongly preferred (specifically Dr. Oligo 48).
• 3-4 years of experience supporting therapeutics and/or diagnostics GMP oligo programs strongly preferred; experience with therapeutics, molecular diagnostics and NGS applications highly desirable.
• 4-6 years of experience in tech transfer of development methods to Manufacturing Operations.
• 3+ years leadership and people management experience in a fast-paced, evolving organization.
• Demonstrated ability to improve throughput, standardize workflows, reduce process variability, and enhance operational efficiency; strong cross-functional leadership in oligonucleotide development environments.