Senior Manager Manufacturing Systems Engineering

Career Category

Engineering

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Be part of Amgen’s newest and most advanced drug substance manufacturing plant. When completed, the Amgen FleX batch facility will combine the latest in single use technologies with traditional stainless steel equipment to allow for maximum flexibility in operations. The FleX Batch facility will not only feature the best in-class drug substance manufacturing technologies with embedded industry 4.0 capabilities, but it will also integrate sustainability innovations to reduce carbon and waste, as part of Amgen’s plan to be a carbon‑neutral company by 2027.

Let’s do this! Let’s change the world! In this vital role, you will oversee the Automation Engineering team, lead technical projects, and drive innovation and support manufacturing’s automation needs. You will solve complex engineering problems and ensure the company’s engineering efforts align with strategic objectives. You will also provide leadership and guidance to the Automation Engineering team supporting 24/7 manufacturing and facility operations.

The Senior Manager Manufacturing System Engineering will join the Facilities & Engineering (F&E) group reporting to the Facilities & Engineering (F&E) Director. This role will partner closely with the corporate engineering team during the design, build, commissioning, and qualification phases. This role will be instrumental in developing automation domain expertise and supporting operational readiness and will develop domain expertise to support operations upon start‑up, focusing on manufacturing automation as well as hiring and training the staff required to support start‑up and operations.

• Build and lead a team of Automation engineering professionals and serve as the main point of contact for the Automation engineering function.

• Support design reviews while partnering closely with the corporate engineering team.

• Execute and support the commissioning and qualification of process equipment automation in alignment with GMP requirements, while working in partnership with global engineering during site installation. Ensure their operational capability is aligned with manufacturing requirements and GMP regulation and on‑time project delivery.

• Collaborate with the site process engineering team to understand key process requirements and develop process control automation solutions primarily utilizing Emerson DeltaV Distributed Control System (DCS).

• Support commissioning and qualification efforts including Automation Installation Verification/Automation Check Out (IV/ACO).

• Partner with various organizational units to support tasks including operational readiness, document reviews, deviation investigation and change controls.

• Provide mentoring to develop and accelerate site technical automation capabilities.

• Lead a team of Automation engineer professionals and serve as the main point of contact for Automation engineering function.

• Accountable for Automation System Administration, Automation System Operating Systems (OS) and Hot Fix assessments and rollout, preventative and corrective maintenance, Automation System…