Senior Process Engineer, Upstream M

Piper Companies is seeking a Senior Process Engineer to join a leading organization within the biopharmaceutical manufacturing industry. This is an onsite, long-term contract opportunity with strong potential for extension and conversion to a full-time employee, based in Holly Springs, NC. The Senior Process Engineer will support upstream manufacturing operations within one of the world's largest end-to-end cell culture manufacturing facilities, providing technical expertise for process optimization, troubleshooting, and manufacturing support.

• Provide technical support for upstream manufacturing operations, including bioreactors, media preparation systems, buffer preparation systems, and hold tanks.
• Support active manufacturing campaigns by troubleshooting process, equipment, and automation-related issues.
• Drive process improvements and optimization initiatives to enhance manufacturing efficiency, reliability, and performance.
• Collaborate cross-functionally with Manufacturing, MSAT, Engineering, Automation, and Quality teams to resolve operational challenges.
• Analyze process data and support investigations, root cause analysis, and corrective actions within a GMP-regulated environment.
• Provide hands-on manufacturing floor support and technical guidance during production activities.

• Bachelor's degree in Chemical Engineering preferred, or a related field in other Engineering disciplines, Biotechnology, and Life Sciences
• 6-10 years of experience in biotech manufacturing, Process Engineering, MSAT, or related manufacturing support roles.
• Strong knowledge of upstream bioprocessing and large-scale manufacturing operations.
• Hands-on experience supporting stainless steel bioprocess equipment in a production environment.
• Demonstrated ability to troubleshoot manufacturing processes, equipment systems, and automation controls.
• Experience providing direct manufacturing floor support preferred over primarily CQV-focused experience.
• DeltaV experience is highly preferred.
• Background in process development or process sciences is a plus.

• $70-$85/hour based on experience.
• Comprehensive Benefits:
  Medical, Dental, Vision, Life Insurance, Paid Time Off, Paid Holidays, and Long-Term Disability coverage.
• Long-term contract with strong potential to convert to a full-time employee.

• Location:
  
  Holly Springs, NC (Onsite)
• Schedule:
  
  Monday-Friday, 8:00 AM - 5:00 PM ET
• Occasional evening support may be required during critical manufacturing activities; however, this is not expected to be frequent.

This position opened for applications on August 21, 2026, and will remain open for at least 30 days from the posting date.