Director Engineering

Career Category Engineering Job Description

If you feel like you’re part of something bigger, it’s because you are. At Amgen, our shared mission—to serve patients—drives all that we do. It is key to our becoming one of the world’s leading biotechnology companies. We are global collaborators who achieve together—researching, manufacturing, and delivering ever-better products that reach over 10 million patients worldwide. It’s time for a career you can be proud of.

Be part of Amgen's newest and most advanced drug substance manufacturing plant.

The Amgen FleX batch facility combines the latest in disposable technologies with traditional stainless steel equipment to allow for maximum flexibility in operations. Not only featuring the best in-class drug substance manufacturing technologies with embedded industry 4.0 capabilities, but also integrating sustainability innovations to reduce carbon and waste.

As Director, Engineering at Amgen North Carolina (ANC), you will lead the site’s Engineering, Automation, Maintenance, and Instrumentation capabilities to deliver safe, compliant, reliable, and efficient drug-substance manufacturing operations. You will establish and execute the long-term technical and organizational strategy required to sustain, improve, and expand a complex GMP manufacturing operation. This role requires a proven site-level leader who can build and lead a high-performing technical organization while balancing safety, GMP compliance, asset reliability, supply continuity, cost, and long-term capability.

In this role, you will:

• Provide strategic and operational leadership for Engineering, Automation, Maintenance, and Instrumentation functions.
• Ensure safe, reliable, and compliant performance of manufacturing equipment, automation systems and instrumentation.
• Establish and execute the site asset-management strategy, including preventive maintenance, predictive maintenance, calibration, reliability, spare-parts, and lifecycle-management programs.
• Lead the engineering compliance program, maintaining inspection readiness and ensuring adherence to cGMP, EHS, quality-system, and applicable regulatory requirements.
• Partner with Site Operations, Quality, Digital/Automation, Supply Chain, and Capital Project Delivery to integrate new assets, resolve technical risks, and implement the long-term site operating strategy.
• Lead technical support for installed systems and equipment, including system ownership, troubleshooting, root-cause analysis, reliability improvement, and sustainable corrective actions.
• Establish governance for maintenance execution and work management, including planning, scheduling, backlog management, work-order quality, contractor oversight, and performance metrics.
• Develop, manage, and forecast departmental operating and capital budgets; prioritize resources against safety, quality, supply, reliability, and lifecycle risks.
• Build and lead a high-performing organization using an appropriate mix of employees, contingent workers, and service providers.
• Set clear accountabilities, develop talent, coach leaders, and create succession plans for critical technical roles.
• Manage strategic service-provider relationships and ensure contractors perform work safely, compliantly, and to required quality standards.
• Escalate significant quality, compliance, supply, safety, and asset-reliability risks to site leadership with clear options and recommendations.
• Drive continuous improvement through data-based decision making, lean maintenance practices, digital tools, reliability engineering, and sustainability initiatives.
• Represent ANC within Amgen’s global engineering, automation, maintenance, and instrumentation networks; adopt and contribute leading practices across the network.
• Make timely, risk-based decisions and trade-offs to protect patients, employees, compliance, and supply.

We are all different, yet we all use our unique contributions to serve patients. The dynamic engineering professional we seek is a leader with these qualifications:

• Doctorate Degree and 4 years of Engineering experience
• Master’s Degree and 8…