Senior Manager: Manufacturing – Material Handling

Career Category Manufacturing Job Description HOW MIGHT YOU DEFY IMAGINATION? You’ve worked hard to become the professional you are today and are now ready to take the next step in your career. How will you put your skills, experience, and passion to work toward your goals? At Amgen, our shared mission—to serve patients—drives all that we do. It is key to our becoming one of the world’s leading biotechnology companies, reaching over 10 million patients worldwide.

Come do your best work alongside other innovative, driven professionals in this meaningful role. Be part of Amgen's newest and most advanced drug substance manufacturing plant. The Amgen FleX Batch facility combines the latest in disposable technologies with traditional stainless‑steel equipment to allow for maximum flexibility in operations. The FleX Batch facility not only features the best in‑class drug substance manufacturing technologies with embedded industry 4.0 capabilities, but it also integrates sustainability innovations to reduce carbon and waste, as part of Amgen's plan to be a carbon‑neutral company by 2027.

Let's do this. Let's change the world. As a Senior Manager of Manufacturing
- Material Handling, you will provide leadership and guidance to the team responsible for 24/7 GMP material handling operations supporting manufacturing across the facility. In this vital role as a member of the Manufacturing leadership team, the Senior Manager, Manufacturing
- Material Handling, will collaborate cross‑functionally to enable the manufacture of drug substance in a new state‑of‑the‑art manufacturing facility. This role is responsible for leading and developing Material Handling Front‑Line Managers who oversee teams supporting the receipt, staging, movement, storage, inventory control, and delivery of GMP materials between the warehouse and manufacturing operations. Additionally, you will be accountable for organizational design, hiring, development, and training compliance of the Material Handling organization to ensure safe, reliable, and uninterrupted manufacturing operations.

The position will also provide leadership and oversight for operational readiness activities to ensure successful facility start‑up and sustained commercial manufacturing performance.

• Develop and retain a diverse, high‑performing Material Handling organization in alignment with operational readiness schedules to support successful facility startup and commercial GMP operations.
• Foster a strong safety, quality, and compliance culture while championing continuous improvement across all Material Handling activities.
• Collaborate as one team with Manufacturing, Warehouse Operations, Quality, Engineering, Supply Chain, Process Development, Automation, and network partners to ensure reliable execution of manufacturing operations.
• Lead the execution and continuous improvement of end‑to‑end material flow processes, ensuring the right materials are available at the right location and time to support uninterrupted manufacturing.
• Oversee inventory accuracy, material reconciliation, cycle counting, and GMP inventory control processes while ensuring compliance with regulatory and internal quality requirements.
• Own the Manufacturing Material Transfer Equipment program, ensuring equipment lifecycle management, availability, qualification, maintenance coordination, and operational readiness.
• Partner with Supply Chain and Warehouse Operations to optimize material staging, replenishment strategies, and production scheduling while minimizing operational risk.
• Provide leadership in troubleshooting operational issues affecting material availability and establish robust escalation and 24/7…