Sr. Principal/Principal Process Engineer - Environmental Control
Job in
Houston, Harris County, Texas, 77246, USA
Listed on 2026-02-16
Listing for:
Eli Lilly and Company
Full Time
position Listed on 2026-02-16
Job specializations:
-
Engineering
Process Engineer, Manufacturing Engineer, Chemical Engineer, Quality Engineering
Job Description & How to Apply Below
US, Houston TXtime type:
Full time posted on:
Posted Todayjob requisition :
R-100144
At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first.
We’re looking for people who are determined to make life better for people around the world.
* At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our 40,000 employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism.
We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.
** Lilly is currently constructing an advanced manufacturing facility for production of API molecules located in Houston, TX. This facility is intended to provide APIs for current and future products, including new modalities. This is a unique opportunity to be a part of the startup team for a greenfield manufacturing site, and the successful candidate will help to build the processes and facility to enable a successful startup into GMP manufacturing operations.
* ** Main Purpose and Objectives:
** The Sr. Principal/Principal Process Engineer for Environmental Control (ECU) will support the Lilly Houston API manufacturing site and will be responsible for tank farm operations, solvent recovery systems, and air emissions systems.
** Responsibilities*
* ** Facility Start-Up:
*** Provide engineering support to the Global Facility Delivery Team (Lilly’s global large scale capital delivery team) with a strong focus on right first time and on-schedule facility start-up. This includes design reviews, process safety assessments, user requirements, C&Q support, unit operation shakedown and start-up, facility operational readiness.
* Define and own relevant aspects of the overall integrated operational readiness plan (e.g. SOP development, maintenance strategy, automation optimization, pre-startup safety reviews, alarm requirements, performance qualification requirements, protocol development, etc.)
* Own the qualified state of equipment for respective area of responsibility
* Support initial operations training requirements as the equipment and area SME
* Develop and implement unit operation and equipment control strategy to sustain and optimize ECU systems in support of manufacturing operations
** Facility Operations:
*** Provide engineering support in ECU operations through application of chemical and/or mechanical engineering fundamentals
* Monitor, assess, and document equipment performance to maintain ongoing qualification
* Develop and maintain the basis of safety for equipment as required
* Identify and implement continuous improvement opportunities related to equipment and processes as core member of cross-functional process team
* Utilize root cause analysis techniques to investigate process and equipment issues and deliver robust and sustainable corrective and preventative actions
* Collaborate with maintenance teams to plan and execute scheduled maintenance activities, including equipment calibration and testing
* Integrate mechanistic modeling, process simulation and analysis into current and future processes to enhance process understanding and control
** Basic Qualifications
*** Bachelors Degree in Engineering (Chemical, Biochemical preferred)
* 7+ years of relevant experience in manufacturing operations (Prefer chemical or pharmaceutical)
* 3+ years’ experience working in Process…
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