Director, Facilities, Engineering, and Maintenance

Join Immatics and shape the future of cancer immunotherapy; one patient at a time!

Immatics is committed to making a meaningful impact on the lives of patients with cancer. We are the global leader in precision targeting of PRAME
, a target expressed in more than 50 cancers. Our cutting-edge science and robust clinical pipeline form the broadest PRAME franchise with the most PRAME indications and modalities, spanning TCR T-cell therapies and TCR bispecifics.

Why Join Us?

• Innovative Environment: Help to pioneer advancements in cancer immunotherapy.

• Collaborative Culture: Be part of a diverse team dedicated to your professional growth.

• Global Impact: Contribute to therapies that make a lasting impact on patients globally.

We are seeking an experienced and forward-thinking Director of Facilities, Engineering & Maintenance to lead all aspects of our US facility operations, engineering strategy, and infrastructure development across our GMP manufacturing and research environments. This role is critical to ensuring our US facilities operate safely, reliably, and in full compliance with regulatory standards. The ideal candidate brings deep technical expertise in biotech or pharmaceutical facility operations, strong leadership capabilities, and a passion for building high performance teams and systems.

FLSA Classification
:
Salaried, Exempt
Schedule
: 8:00 AM - 5:00 PM;
Monday to Friday;
On-site
Reports to
:
Chief Operating Officer
Location
: 13203 Murphy Road, Suite 100, Stafford, TX 77477

What You'll Do:

As a Director of Facilities, Engineering & Maintenance
, you will play a key role in supporting our US facility operations:

• Develop and execute the long-term facility engineering & maintenance strategy to support company growth, GMP manufacturing capacity, and R&D operations.

• Accountable for scaling the facility infrastructure for commercial manufacturing, inspection readiness, uptime and cost-efficient operation.

• Lead capital planning, budgeting, and prioritization for facility upgrades, expansions, and construction.

• Serve as the primary engineering advisor to senior leadership, providing insights on infrastructure readiness, risk, and operational performance.

• Oversee the operation, maintenance, and lifecycle management of all critical building systems, including HVAC, clean rooms, utilities, automation, and process equipment.

• Ensure uninterrupted operation of GMP and laboratory facilities through robust preventive and predictive maintenance programs, and establishing an alarm escalation chain.

• Establish engineering standards, SOPs, and best practices to ensure consistent, compliant, and efficient facility operations.

• Ensure all facility systems meet regulatory requirements (FDA, EMA, ISO, cGMP, CLIA) and maintain audit readiness.

• Partner with Quality Assurance to manage deviations, CAPAs, change controls, and validation activities related to facility infrastructure.

• Partner with Computer System Validation to manage validation of new equipment.

• Oversee qualification and validation of utilities and equipment (e.g., HVAC, WFI, clean steam, compressed gases, BMS/EMS).

• Lead the planning, design, and execution of facility engineering projects, including cleanroom builds, utility upgrades, and equipment installations.

• Manage external engineering firms, contractors, and vendors to ensure projects are delivered on time, within budget, and to specification.

• Implement strong project governance, documentation, and risk management practices.

• Responsible for EHS-related compliance on site.

• Ensure site security.

• Drive sustainability initiatives related to energy efficiency, waste reduction, and environmental impact.

• Oversee emergency response systems, business continuity planning, and facility risk assessments for the facilities, engineering & maintenance department.

• Build, mentor, and lead high performing multidisciplinary engineering team.

• Foster a culture of accountability, continuous improvement, and cross functional collaboration.

• Develop training programs to ensure staff competency in GMP, safety, and technical disciplines.

• Oversee vendor relationships for facility services, maintenance contracts, and engineering support.

• Negotiate service agreements and ensure vendor performance meets operational and compliance standards.

• Manage departmental budgets, cost controls, and resource allocation.

Required Experience and

Education:

• Bachelor's degree in Engineering (Mechanical, Electrical, Chemical, or related field).

• 10+ years of facilities, engineering & maintenance experience in biotech, pharmaceutical, or other regulated life science environments.

• 5+ years of leadership experience managing engineering or facility operations teams.

• Demonstrated experience in at least some of the following: leading GMP facility start-up or expansion projects, managing critical utilities and clean rooms in regulated manufacturing, running maintenance/reliability programs, handling audits/inspections, and building teams in a fast-growth biotech environment.

• Strong knowledge of GMP…