Associate Scientist, Downstream Process Development

Kelly® Science & Clinical is seeking an Associate Scientist for a contract opportunity with one of our clients, a gene therapy biotechnology company focused on neurological disorders. If you are driven by the prospect of translating cutting-edge scientific discoveries into tangible advancements and are poised to advance your career, join us as we pioneer progress in the biotechnology and medical device industries.

Workplace: Onsite in Houston, TX

Position Title: Associate Scientist, Downstream Process Development

Position Type: 6-month contract

Pay rate: $30-40 per hour

Associate Scientist, Downstream Process Development – Gene Therapy

Are you ready to play a vital role in transforming the future of neurological disease treatment? An innovative, clinical-stage biopharma company is seeking a talented Associate Scientist in Downstream Process Development to join its fast-growing team in Houston. This is a unique opportunity to advance your career in gene therapy, supporting a rapidly expanding pipeline and world-class manufacturing environment.

This hands-on technical role supports the design, execution, and optimization of breakthrough gene therapy products. Reporting to the Associate Director, Downstream Process Development, you will contribute across a spectrum of viral vector purification activities—empowering the company’s pipeline from research through clinical and commercial production.

Be part of a collaborative and mission-driven culture that is unwavering in its commitment to patients, innovation, and scientific excellence.

• Execute routine and complex viral vector purification, from buffer preparation and sampling to small-scale purification runs and GMP batch execution.
• Support process development operations, including development and toxicology production runs, reagent prep, inventory control, and lab upkeep.
• Draft and review critical documentation, including SOPs, batch production records, process forms, and laboratory records, adhering to best practices in biotechnology and compliance.
• Collaborate cross-functionally with analytical and upstream teams to define and deliver critical quality attributes and process performance for AAV purification.
• Maintain accurate laboratory protocols and data capture, participating in inventory and equipment management, waste disposal, and lab safety procedures.
• Stay engaged with the latest advances in viral vector process development and proactively contribute to the success of the process development team.

• BSc in Biological Science or related discipline
• 1-2 years’ experience in a biotechnology or biopharma environment preferred
• Practical experience in basic laboratory operations related to virus/protein purification, buffer preparation, and aseptic technique
• Familiarity with chromatography and filtration purification methods; AKTA chromatography experience preferred
• Hands-on experience with viral vector bioprocessing, especially AAV, is an advantage
• Comfortable working in regulated environments (GLP/GMP); GMP experience is a plus
• Understanding of bioprocess documentation (SOPs, batch records) and regulatory expectations (FDA/EMA/cGMP a plus)
• Proven team player with strong organizational, communication, and problem-solving skills
• Tech-savvy with proficiency in MS Office, accurate documentation practices, and attention to detail

• Grow with a forward-thinking company at the cutting edge of gene therapy for neurological diseases
• Collaborate with industry experts and contribute to life-changing therapies
• Advance your skills in a highly supportive, innovation-focused culture
• Be part of a Houston-based organization with an end-to-end manufacturing footprint, setting the stage for personal and professional growth

Take your next step in the gene therapy revolution. Apply your expertise in downstream process development to truly make a difference for patients and families facing rare diseases.