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Associate Vice President, Infrastructure & Operations

Job in Houston, Harris County, Texas, 77246, USA
Listing for: University of Texas MD Anderson Cancer Center
Full Time position
Listed on 2026-07-17
Job specializations:
  • IT/Tech
    Cloud Computing: Infrastructure & Operations, IT Project Manager
Salary/Wage Range or Industry Benchmark: 311000 - 365000 USD Yearly USD 311000.00 365000.00 YEAR
Job Description & How to Apply Below

The mission of UT MD Anderson is to eliminate cancer in Texas, the nation, and the world through outstanding programs that integrate patient care, research and prevention, and through education for undergraduate and graduate students, trainees, professionals, employees and the public.

The Associate Vice President (AVP), Infrastructure and Operations is the senior-most digital technology operations leader within MD Anderson's Technology, Data & Innovation (TDI) division, reporting directly to the VP, Chief of Digital Operations and Infrastructure (CDOI). This role carries full accountability for the architecture, delivery, reliability, and continuous evolution of the physical and digital infrastructure that underpins every mission of MD Anderson - patient care, cancer research, clinical trials, education, and administration.

The AVP leads a broad and deeply technical portfolio spanning Infrastructure Engineering, Cloud Services, Data Center Management & Operations, Service Delivery, and Super Computing. This executive is responsible for ensuring that mission-critical systems are available, performant, secure, and able to scale to the demands of a world-class comprehensive cancer center.

As a key member of the TDI senior leadership team, the AVP partners across the CDOI peer group; including the Chief Innovation Officer, Chief Data & Analytics Officer, Chief Information Security Officer, and Head of the PMO; to align infrastructure strategy with enterprise digital transformation objectives, AI adoption, Epic infrastructure optimization, PACS infrastructure and operations, high-performance computing and storage needs of researchers, and the ongoing TDI operating model transformation.

The successful candidate is a proven infrastructure and operations executive who combines deep technical command with enterprise leadership capability. They bring a track record of modernizing large-scale I&O functions, driving cloud adoption at scale, delivering measurable improvements in reliability and cost, and building high-performing organizations in complex, mission-driven environments.

Key Functions
  • Define, own, and continuously evolve the enterprise infrastructure and operations strategy aligned to MD Anderson's multi-year digital transformation roadmap and TDI's target operating model.
  • Drive infrastructure modernization including on-premises, cloud-native architecture, hybrid cloud management, software-defined infrastructure, and network transformation.
  • Evaluate and adopt emerging technologies - including AI/ML-enabled operations (AIOps), observability platforms, and automation tooling - to continuously improve service quality, speed, and cost.
  • Define and enforce enterprise-grade availability, performance, and resilience standards across all infrastructure domains, championing ITSM frameworks anchored in ITIL best practices.
  • Establish and maintain robust disaster recovery and business continuity capabilities, working in close partnership with Operations leadership, Risk Management, and TDI leaders to ensure institutional digital resilience.
  • Provide executive oversight for MD Anderson's hybrid cloud strategy, including public cloud (AWS, Azure, GCP), private cloud, and co-location environments including TACC.
  • Direct the Data Center Management & Operations function, ensuring facilities meet clinical, research, and administrative reliability requirements with best-in-class power, cooling, and physical security practices.
  • Oversee the super computing function, ensuring high-performance compute (HPC) and research computing capabilities support cancer research, genomics, and AI-driven discovery at the forefront of the institution's scientific mission.
  • Lead the Service Delivery function responsible for end-user computing, service desk operations, device lifecycle management, and the overall digital experience of MD Anderson faculty, clinicians, researchers, and staff.
  • Drive continuous improvement in end-user satisfaction and service delivery efficiency, leveraging automation, AI, and self-service mechanisms to empower end users.
  • Work in close collaboration with the Chief Information Security Officer (CISO) to ensure all infrastructure domains incorporate, enforce, and continuously improve security architecture, controls, and vulnerability management practices.
  • Embed security-by-design into infrastructure provisioning, change management, and architecture review processes, maintaining governance frameworks that support HIPAA, HITECH, and applicable Texas state information security mandates.
  • Develop, own, and actively manage the I&O budget, applying a total cost of ownership lens to all infrastructure investment decisions and driving cost optimization through consolidation, automation, and cloud right-sizing.
  • Lead strategic vendor and partner relationship management for I&O, including major technology vendors and managed service providers, negotiating to maximize institutional value and service quality.
  • Build, develop, and retain a high-performing…
Position Requirements
10+ Years work experience
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