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Senior Manufacturing Associate - Second Shift

Job in Houston, Harris County, Texas, 77030, USA
Listing for: Immatics NV
Full Time position
Listed on 2026-06-02
Job specializations:
  • Manufacturing / Production
    Medical Device Industry
Job Description & How to Apply Below
Join Immatics and shape the future of cancer immunotherapy; one patient at a time!

Immatics is committed to making a meaningful impact on the lives of patients with cancer. We are the global leader in precision targeting of PRAME
, a target expressed in more than 50 cancers. Our cutting-edge science and robust clinical pipeline form the broadest PRAME franchise with the most PRAME indications and modalities, spanning TCR T-cell therapies and TCR bispecifics.

Why Join Us?
  • Innovative Environment: Help to pioneer advancements in cancer immunotherapy.
  • Collaborative Culture: Be part of a diverse team dedicated to your professional growth.
  • Global Impact: Contribute to therapies that make a lasting impact on patients globally.
Role Overview

We are seeking a Senior Manufacturing Associate to support our CMC-GMP Manufacturing team. In this role, you will lead and execute complex, time-sensitive cell processing and testing activities for patient-derived cellular products in a clinical manufacturing environment. You will be responsible for ensuring compliance with GMP standards, maintaining product integrity and sterility, and overseeing accurate documentation and batch execution. As a senior team member, you will also provide technical guidance, support process improvements, and contribute to maintaining high operational standards across manufacturing activities.

Schedule
: 1430 - 2300;
Monday to Friday
Reports to
:
Manufacturing Manager
Location
: 13203 Murphy Road Suite 100 Stafford, TX 77477

Basic Qualifications:
  • Associate's or Bachelor's degree in a scientific field (e.g., biology, biotechnology, or related discipline)
  • 4+ years of experience in GMP-regulated manufacturing, preferably in cell therapy or biologics
  • Demonstrated experience executing aseptic processing and working in cleanroom environments (Grade A-D)
  • Proven ability to maintain compliant documentation in accordance with ALCOA++ and cGDocP standards
  • Experience identifying deviations and supporting investigations, CAPAs, and quality systems
Preferred Qualifications:
  • Bachelor's degree in a scientific field
  • Experience in cell therapy manufacturing, including cell culture, cryopreservation, and cell processing techniques
  • Familiarity with GLP, GTP, and industry standards (e.g., FACT, CAP, CLIA)
  • Experience supporting validation activities (IQ/OQ/PQ) and change control processes
  • Advanced troubleshooting skills and ability to resolve complex manufacturing or equipment issues
  • Experience mentoring or training junior staff and contributing to team development
  • Demonstrated ability to drive process improvements in a GMP-regulated environment
In this role you will:
  • Execute and verify cell processing activities, including cell culture, enrichment, cryopreservation, thawing, and washing
  • Perform manufacturing operations in compliance with GMP, GLP, GTP, and applicable regulatory standards
  • Maintain accurate, compliant documentation and batch records in line with ALCOA++ and cGDocP requirements
  • Ensure aseptic handling and cleanroom compliance to maintain product sterility and integrity
  • Identify, document, and support investigation of deviations, including CAPA implementation
  • Perform calculations, equipment maintenance, and routine manufacturing support activities
  • Lead manufacturing runs, mentor junior team members, and contribute to continuous improvement initiatives
What do we offer?

At Immatics, we believe in investing in our team's health, safety and well-being. Here's what you can expect if you join Immatics:

Comprehensive Benefits
:
  • Competitive rates for Health, Dental, and Vision Insurance
  • 4 weeks of vacation, granted up front each year and prorated for first and last year of employment.
  • 12 company paid holidays
  • 7 days of sick time
  • 100% employer-paid life insurance up to at 1x annual salary, up to one hundred thousand dollars
  • 100% employer-paid short- and long-Term disability coverage
  • 401(k) with immediate eligibility and company match...
  • The company will match 100% of your contributions up to 3% of your base salary for the first two years of employment, 4% for years 2-3 of employment, and up to 5% of your salary from the fourth year onward of continued employment.
  • Partially paid parental leave…
Position Requirements
10+ Years work experience
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