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Lead, Research​/Development, Research Scientist

Job in Houston, Harris County, Texas, 77030, USA
Listing for: Houston Methodist Academic Institute
Full Time position
Listed on 2026-07-01
Job specializations:
  • Research/Development
    Research Scientist, Clinical Research
  • Healthcare
    Clinical Research
Job Description & How to Apply Below
Position: COME LEAD WITH US

Computational Research Associate

Computational Research Associate is available for a highly motivated candidate with a background in bioinformatics and a passion for exploring the epigenomic alterations in cancer progression and therapy resistance. The successful candidate will apply and analyze high-throughput sequencing datasets, including ChIP-seq, ATAC-seq, RNA-seq, and Hi-C, to uncover regulatory mechanisms in cancer. A M.S. or Ph.D. degree in computational biology, bioinformatics, biostatistics, data science, or a related field is preferred.

The candidate should have strong training in programming, particularly in R and/or Python, and a demonstrated interest in applying computational and statistical methods to complex biological datasets. Experience with single-cell data analysis is highly desirable. The successful applicant will join a collaborative and interdisciplinary research team and contribute to cutting-edge basic and/or translational research.

Projects will focus on the functional epigenomics with two directions towards: (1) understanding the role of epigenetic aberrations in early tumorigenesis, disease progression and the development of therapy resistance, and (2) searching for biomarkers and specific therapeutic targets for personalized cancer medicine.

Qualifications:

  • Master's degree in related field or terminal degree with two years post-doctoral experience

Experience:

  • Five years experience, depending on education level

Skills and Abilities:

  • Demonstrates the skills and competencies necessary to safely perform the assigned job, determined through ongoing skills, competency assessments, and performance evaluations
  • Sufficient proficiency in speaking, reading and writing the English language necessary to perform the essential functions of this job, especially with regard to activities impacting patient or employee safety or security
  • Ability to effectively communicate with patients, physicians, family members and co-workers in a manner consistent with a customer service focus, and application of positive language principles
  • Ability to work independently
  • Capable of handling challenging/difficult situations
  • Demonstrates sound judgment and executes analytical skills

Essential Functions:

  • Assigns and reviews the work and outcomes for projects completed by assistants.
  • Contributes to a positive work environment and contributes to a dynamic, team-focused work unit that actively helps one another to achieve optimal department results. Collaborates with all members of the research team by actively communicating and reporting pertinent information as it relates to an assigned system(s) in a comprehensive manner.
  • Provides contributions towards the improvement of department scores for turnover/retention/employee engagement.
  • Analyzes data for research grants and publications. Prepares scientific presentations for department meetings.
  • Completes/performs research experiments and incorporates novel procedures and methods into research experiments as appropriate (low to medium complexity).
  • Maintains accurate records of all research and data collection.
  • Establishes and maintains quality control of project operations.
  • Writes and maintains regulatory and safety committee applications/protocols.
  • Identifies opportunities for corrective action and process improvement providing recommendations and contributes to meeting departmental and hospital targets for quality and safety.
  • Uses resources efficiently; does not waste supplies. Self-motivated to independently manage time effectively and prioritize daily tasks, minimizing incidental overtime.
  • Assists with ensuring orders are on appropriate grants.
  • Participates in grant writing.
  • Determines specific research project goals and objectives to be attained. Assumes responsibility and oversight for those goals and objectives.
  • Seeks opportunities to identify developmental needs of self and takes appropriate action. Ensures own career discussions occur with appropriate management. Completes and updates the individual development plan (IDP) on an ongoing basis.

Supplemental Requirements:

  • Uniform:
    No
  • Scrubs:
    Yes
  • Business professional:
    Yes
  • Other (department approved):
    No
  • On Call
    * No
  • May require…
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