Project Chemist; Mass Spectrometry

We are seeking a motivated Project Chemist to support routine LC‑MS–based analysis in a fast‑paced laboratory environment. This role is responsible for the timely and reliable execution of LC‑MS/MS workflows, including sample preparation, instrument operation, troubleshooting, and data review.

• Perform routine LC‑MS based assays including peptide mapping, intact mass analysis and protein/small molecule quantitation in a timely and compliant manner.
• Prepare samples, standards, mobile phases, buffers, and other laboratory solutions.
• Operate and maintain LC‑MS/MS and HPLC/UHPLC systems following SOPs.
• Conduct routine analytical runs and monitor instrument performance.
• Review, organize, interpret, and document analytical data and laboratory records.
• Identify and report unexpected test results, providing initial troubleshooting where applicable.
• Perform system suitability, calibration, and QC checks.
• Troubleshoot basic instrument and method issues.
• Maintain laboratory cleanliness, inventory, and organization.
• Support method optimization and validation activities as appropriate.
• Collaborate with cross‑functional team members to support project timelines and deliverables.

• Bachelor’s or Master’s degree in chemistry, analytical chemistry, biochemistry, or related field.
• Hands‑on experience with LC‑MS/MS instrumentation and workflows.
• Experience with mass spectrometry–based protein and peptide characterization, including sample preparation, instrument operation, and data analysis.
• Experience with LC‑MS/MS quantitation using MRM and/or SIR acquisition modes.
• Hands‑on experience with HPLC or UHPLC systems.
• Familiarity with biological and/or chemical sample matrices.
• Experience with basic wet chemistry and sample preparation techniques.
• Familiarity with GMP (Good Manufacturing Practices) and applicable regulatory requirements (e.g., FDA, ICH).
• Strong attention to detail, organizational skills, and documentation practices.
• Comfortable working with laboratory software and data management systems.
• Ability to work independently as well as collaboratively in a team environment.
• Strong verbal and written communication skills.

• Hands‑on experience with HPLC, UPLC, and MS instrumentation.
• Knowledge of peptide synthesis and purification techniques.
• Experience in a pharmaceutical or biotechnology setting.
• Understanding of protein chemistry and post‑translational modifications.

• Certification in HPLC.

Equal Opportunity

Employer:

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