Staff Scientist

Summary The Jorgez Laboratory in the Department of Urology at Baylor College of Medicine is seeking a highly motivated Staff Scientist to join an NIH-funded research program investigating the molecular and developmental mechanisms underlying testicular dysfunction and infertility in a Wnt4 conditional knockout (Wnt4-cKO) mouse model. This position offers the opportunity to work at the interface of developmental biology, reproductive endocrinology, and cutting-edge spatial and 3D imaging technologies, within a collaborative, well-resourced research environment in the Texas Medical Center.

• Design and execute experiments using mouse models, including breeding colony management and genotyping
• Perform advanced 3D and spatial imaging (confocal, LSFM, Xenium spatial transcriptomics) and associated computational image analysis
• Conduct cellular and molecular assays including, immunohistochemistry, proteomic profiling, and tissue-derived cell culture-based functional studies
• Analyze, interpret, and present complex multimodal datasets integrating imaging, transcriptomic, and proteomic data
• Prepare manuscripts for peer-reviewed publication and contribute to grant progress reports and future funding applications
• Maintain reagents and supply for experiments
• Teach techniques, procedures, and experimental design to other members of the lab
• Communicate research results in group meetings, national or international conferences
• Plan, direct, and conduct research experiments
• Develop research techniques and perform applications required for specific research projects
• Perform other job-related duties as assigned

• Doctoral Degree. Experience may not be substituted in lieu of degree.
• Three years of post doctoral research experience.

• Experience with advanced 3D imaging modalities (light sheet fluorescence microscopy, confocal microscopy) and/or spatial transcriptomics platforms (e.g., Xenium, Visium)
• Background in male reproductive biology, testicular development, or endocrinology

• Experience working on the Wnt/Bcatenin signaling pathway
• Experience with bioinformatic analysis of transcriptomic or proteomic datasets
• Prior experience with animal surgical techniques (e.g., orchidopexy models)

This position is not eligible for visa sponsorship. Candidates must be legally authorized to work in the United States at the time of application and throughout the duration of employment.

Baylor College of Medicine is an Equal Opportunity/Affirmative Action/Equal Access Employer.