Director of Clinical Science and Applied Research

Director of Clinical Science and Applied Research

Houston, Texas, United States;
Houston, Texas, United States;
Motif - Remote

Motif is a medical device startup based in Houston, Texas. We are designing and developing minimally invasive electronic solutions for serious mental health conditions. Powered by our patent‑pending methods for wireless power and data transmission, our goal is to create the smallest implantable brain stimulator to treat people with mental health disorders.

We are an early‑stage startup with funding from venture capital firms, grants, and private angel and founder investments.

Motif’s technology stack consists of a small implant that is wirelessly powered via magnetic fields from an external wearable transmitter, configured and controlled from a programming interface. It delivers novel stimulation therapy to cortical targets and will evolve to record biomarkers of symptoms, disease state, and therapy response.

We are currently completing the development of our first minimally invasive neural stimulation system and preparing for future versions with additional functionality based on our platform technology.

We are seeking a cross‑functional strategic leader to oversee clinical evidence generation and external research partnerships. If you have a passion for translating early‑stage neurotechnology into therapies that reach patients, apply now to be part of our dedicated team. Lead the clinical roadmap from early feasibility through reimbursement while shaping the scientific narrative for a new class of psychiatric therapy.

Job Location:

Remote with occasional visits to Motif Headquarters in Houston, Texas

• Do you believe openness and honesty are key to team success?
• Do you enjoy learning and are curious about how and why things work?
• Do you like challenging the conventional way of doing things to find efficiencies and new ways of working?

If yes to the above, then come work with Motif! We are highly dedicated people with a passion for neurotechnology, clinical product development, and putting the patient first. We are looking for people with the same energy who will thrive in a high growth - high autonomy environment.

• Develop and own the clinical roadmap
• Define the end‑to‑end evidence generation strategy from early feasibility studies through to successful reimbursement decisions
• Integrate regulatory and reimbursement requirements into study design to ensure clinical data supports both approval and coverage
• Partner with leadership to align the clinical roadmap with company strategy, financing milestones, and product development timelines
• Oversee clinical development projects and grants
• Provide oversight of active clinical studies, ensuring programs are delivered on time, on budget, and to protocol
• Identify, secure, and manage non‑dilutive funding sources, including federal grants and foundation support for evidence development (clinical and preclinical) programs
• Oversee grant‑funded programs end‑to‑end, including reporting, milestone tracking, and renewals
• Represent the company externally and build the scientific community
• Represent the company at scientific and medical meetings, presenting data and shaping the clinical narrative for our platform
• Build and maintain peer‑level relationships with key opinion leaders in psychiatry, neuromodulation, and related fields
• Establish and manage external research partnerships with academic investigators and clinical collaborators
• This is not an exhaustive list of duties and you may be asked to perform different tasks if your role within or the objectives of the organization changes.

• 10+ years of experience in clinical…