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Director, Computational HitGen ​/ LeadGen Team Lead

Job in Great Lakes, Lake County, Illinois, 60088, USA
Listing for: AbbVie
Full Time position
Listed on 2026-08-09
Job specializations:
  • Research/Development
    Research Scientist
Job Description & How to Apply Below
Location: Great Lakes

Job Title

This position brings an opportunity to make innovative contributions that will define how Abb Vie leverages AI-native drug discovery across our small molecule portfolio.

Responsibilities

Provide strategic thought leadership to amplify CDD's impact on the small molecule pipeline:

  • Lead development of a cohesive collection of cutting-edge methods and workflows, to comprehensively address Abb Vie's small molecule portfolio needs (methods for predicting binding affinities of diverse chemo types, for predicting pharmacological properties for diverse chemo types (PK parameters, etc.), and for rapidly sampling both enumerated and AI-generated chemical spaces
  • Work closely with the small-molecule leadership teams to identify and address gaps where computational predictions are needed
  • Advance drug discovery expertise across CDD and collaborate with cross-disciplinary teams from R&D and Information Research to advance programs and ensure computational capabilities are best implemented across programs

Direct activities of the HGLG Team to enable program-level decision making:

  • Across Abb Vie's early-stage small molecule portfolio, provide leadership and guidance that will deliver computational tools and workflows to achieve desirable hit/lead criteria. Role will be integral for ensuring alignment across functions and with the longer-term organizational and broader AI-native drug discovery strategies
  • Guide HGLG team members in benchmarking experiments to evaluate models' performance and domain of applicability for Abb Vie's small molecule portfolio
  • Establish processes for selecting specific approaches that best suit project needs

Build CDD's reputation for impact:

  • Proactively demonstrate leadership by providing expert advice and shared knowledge with direct reports, peers, and senior management
  • Present program updates and research strategies to functional and non-functional leaders as well as potential and existing partners
  • Maintain awareness of emerging literature and science in the field and author scientific disclosures/publications
  • Maintain scientific presence outside Abb Vie with appropriate publication and conference abstract submission highlighting innovative learnings in AI-native drug discovery
Qualifications
  • Bachelor's Degree or equivalent education in science-related field with extensive (typically > 18 years) of related work;
    Master's Degree or equivalent education with extensive (typically > 16 years) of related work;
    PhD in Science or related field with typically 10+ years of related work experience
  • Demonstration of successful coaching/mentoring and people management
  • Demonstration of setting and driving strategy, in the context of leading a global team
  • Highly organized and self-directed, experience leading multiple complex simultaneous research programs or initiatives
  • Knowledge and experience in modern computational approaches for drug discovery
  • Excellent written and verbal communication, as well as critical evaluation and data-driven decision making
  • Strong analytical and problem-solving skills with demonstrated ability to think critically and creatively, and provide solutions both individually and collaboratively with internal experts
  • Proven team leadership and management abilities, including experience mentoring, guiding, supervising, and developing scientific personnel with various backgrounds and training levels
  • Highly collaborative, team-oriented, and considerate of the needs of others
  • Strong interpersonal skills and ability to collaborate with diverse groups within the organization and external partners
  • Ability to create an inclusive environment where diverse ideas, viewpoints and backgrounds are valued; willingness and ability to lead inclusively and demonstrate a commitment to listen and consider all points of view
Additional Information
  • The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range.

    This range may be modified in the future.
  • We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.
  • This job is eligible to participate in our long-term incentive programs.

Abb Vie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

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