Mass Spec Scientist (contractor) - Large Molecule Characterization

We are a cutting-edge start-up biotechnology company developing the next generation of therapeutic bispecific antibodies focused on extracellular protein degradation. We are seeking a temporary scientist level contractor to join our mass spec team starting in August. The candidate will apply state-of-the art to characterize protein therapeutics as well as analyze complex biological samples in proteomics studies.

• Operate and maintain Orbitrap mass spectrometer and HPLC
• Characterize antibody therapeutics using mass spec, including intact mass measurement, bispecific antibody chain pairing analysis, N-glycosylation analysis and PTM profiling through peptide mapping
• Assist with proteomics experiments from study design, sample preparation to data analysis to understand the mechanism of action for novel therapeutic drugs
• Maintain detailed experimental record
• Communicate and collaborate across a diverse interdisciplinary team

• BS degree required
• Must be able to work onsite daily
• Experience with independent operation and maintenance of Orbitrap mass spectrometer and HPLC
• In depth knowledge and extensive hands-on industrial experience with intact mass measurement, subunit analysis, peptide mapping, and N-glycosylation profiling
• Strong understanding of antibody sequence liability and data interpretation in forced degradation samples
• Experience with Xcalibur, Qual Browser, Bio Pharma finder and Byos is preferred
• Experience with bispecific antibody and ADC is preferred
• Experience with proteomics is a bonus but not required

The expected salary range for this role is $70 - $85 per hour

The above pay range is what we reasonably expect to pay for this position. Individual compensation is based on various factors, including experience, education, skillset, and geographic location.

All qualified applicants will receive consideration without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law.