Executive Medical Director - Physician - Early Clinical Development, Aesthetic Medicine

At Lilly, the work is demanding because patients are waiting. We unite caring with discovery to help make life better for people around the world, knowing that every decision, every detail, and every day matters. Headquartered in Indianapolis, Indiana, our over 50,000 employees around the globe take on complex challenges to discover and deliver life-changing medicines, strengthen how health is understood and managed, and support the communities we serve.

This is hard, urgent, selfless work—but it’s work worth doing. If you’re driven by purpose and ready to bring your best to work that truly matters for patients, we invite you to join us.

We are seeking a high-impact physician scientist and emerging industry leader to join our Aesthetic Medicine team as Executive Medical Director, Early Clinical Development. This role is designed for a clinical translational leader ready to step into enterprise influence, bridging the critical gap between discovery science and clinical application, driving the development of transformational medicines for people seeking aesthetic and dermatologic treatments.

• Collaborate with discovery, translational medicine, and clinical teams to develop and refine therapeutic hypotheses for aesthetic medicine indications, including skin health and quality, facial aesthetics, and body aesthetics
• Participate in prioritization of target and modality selection, integrating scientific rigor with clinical feasibility, unmet needs, and commercial potential, with particular attention to transformational potential of proposed programs
• Evaluate and diligence external discovery and early clinical opportunities for potential partnerships or acquisitions
• Provide scientific and clinical expertise to portfolio strategy to ensure a robust pipeline of transformational medicines in aesthetic medicine
• Act as a visible strategic leader within the aesthetic medicine portfolio, influencing direction, investment decisions, and development priorities

• In collaboration with stakeholders, design early clinical studies that efficiently test therapeutic hypotheses
• Collaborate with clinical pharmacology, biostatistics, regulatory affairs, operations, Health Economics and Outcomes Research (HEOR), and other stakeholders to optimize study design and execution
• Integrate translational endpoints, biomarker strategies, and validated aesthetic scales and patient-reported outcome measures to accelerate and maximize learning from early clinical studies and enable early decision-making
• Contribute to regulatory interactions, including pre-IND, IND submissions, interactions with ex-US health authorities, as well as regulatory strategy development
• Monitor patient safety and ensure compliance with GCP, FDA, ICH guidelines, and company policies
• Drive innovative experimental medicine approaches and accelerate progression from first-in-human through proof-of-concept

• Serve as scientific and medical expert across multiple therapeutic programs simultaneously
• Lead early clinical strategy in cross-functional teams through matrix influence, aligning diverse stakeholders around common objectives
• Facilitate decision-making processes across discovery, development, and commercial functions
• Mentor and develop junior team members while building scientific capabilities across the organization
• Operate as a culture-shaping leader who elevates performance, accountability, and collaboration across teams

• Establish and maintain relationships with key opinion leaders and scientific experts in aesthetic medicine, dermatology, and plastic surgery
• Represent Lilly at scientific conferences, advisory…