Advisor​/Senior Advisor - Oligonucleotide Chemistry

Location: Indianapolis

Advisor/Senior Advisor - Oligonucleotide Chemistry page is loaded## Advisor/Senior Advisor - Oligonucleotide Chemistry locations:
US, Indianapolis INtime type:
Full time posted on:
Posted Todayjob requisition :
R-98047

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first.

We’re looking for people who are determined to make life better for people around the world.

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our 49,000 employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism.

We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world.

Lilly is passionate about the discovery, development and commercialization of potential new medicines that will impact and improve the lives of patients. Lilly Genetic Medicines is an innovation-focused organization striving to identify, develop and apply the most cutting-edge technologies to deliver maximum benefit to our patients. Our agile and diverse team strives to operate as an autonomous ‘biotech-like’ company within the walls of Lilly.

The Lilly Genetic Medicines (LGM) Team is looking for a collaborative, creative, and energetic problem solver to join a multidisciplinary team at the front edge of innovation.  They will join our fast-paced, interdisciplinary team as we utilize novel RNA/oligonucleotide based therapeutic modalities to enhance the Lilly portfolio. The successful applicant will utilize their knowledge and technical expertise to accelerate the core capabilities of large-scale oligonucleotide synthesis of internal RNAi-based clinical candidates.  

We want you on our team!

Responsibilities:
* Lead the Lilly Genetic Medicines discovery oligosynthesis scale-up team to accelerate Lilly RNAi Therapeutics from pre-clinical to clinical development
* Utilize comprehensive expertise in oligonucleotide synthesis methodologies to support Lilly Genetic Medicines and further develop internal capabilities and team growth through effective coaching, mentorship, and leadership.
* Collaborate with members of the RNAi discovery chemistry teams to validate and execute requirements for oligonucleotide synthesis from 150umol to 6mmol scales including communication of relevant information and results to project leads and/or cross functional organizations within Lilly to ensure seamless operation of the scale-up team.
* Actively support our efforts toward the discovery of lead drug candidates and lead at the interface with our CMC and Development teams to provide essential materials for key studies and effectively communicate technical insights to the development team.
* Demonstrate expertise in modern synthetic organic and nucleic acid chemistry, striving to improve methods, develop new technologies, and address synthetic oligonucleotide challenges across a diverse portfolio
* Oversee and prioritize the work of scale-up team members to meet critical timelines.
* Value diverse perspectives and experiences for effective solutions. Motivate team members to take initiative, own outcomes, and share expertise on complex technical challenges.
* Guide teams through unclear situations, adapt efficiently to changes, and evaluate and implement effective approaches to completing tasks.

Basic Qualifications:

* PhD degree in a relevant scientific discipline with 2+ years of experience (oligonucleotide synthesis experience, solid phase synthesis) or MS degree with 5+ years of experience (oligonucleotide synthesis experience,…