Principal Scientist, Biotransformation

Job Summary

This role provides scientific and technical leadership across global laboratory operations, driving continuous improvement, overseeing technology transfer, and supporting complex metabolism study initiatives. You will independently conduct and interpret in vitro and in vivo metabolite identification studies and lead technical efforts that elevate quality and efficiency.

• Lead global technical initiatives, continuous improvement efforts, and operational harmonization
• Independently perform in vitro and in vivo metabolite  and assign metabolite structures using MS/MS data
• Oversee complex study designs, technology transfer activities, and validation projects
• Collaborate with project teams and clients to support study setup and scientific discussions
• Conduct quality investigations, support CAP/EQAS responses, and drive preventative actions
• Evaluate new technologies, instrumentation platforms, and process enhancements
• Provide training, technical guidance, and mentorship to laboratory staff

Bachelor’s Degree in medical, laboratory science, chemical, biological, or related field.

• Extensive experience with MS and MS/MS data interpretation for metabolite identification
• Proficiency in conducting metabolic profiling and complex in vitro/in vivo studies
• Hands‑on experience in regulated laboratory environments supporting drug development

Other Equivalent combination of education, training, and experience may be accepted in lieu of degree

• Strong understanding of drug development processes, regulatory expectations, and cross‑functional dependencies
• Ability to analyze complex data, troubleshoot technical challenges, and drive process improvements
• Excellent communication skills with the ability to interface effectively with clients and internal teams

We put our employees at the center of everything we do and are committed to providing them, and their families, with benefits that meet their diverse and changing needs. We invest in integrated benefits programs and resources to take care of our employees’ physical, mental and emotional, financial and social well‑being so they can thrive at home and at work, at any stage of their well‑being journey.

To learn more about our benefits, visit

If you’re looking to unleash your potential, join IQVIA Laboratories to help make the extraordinary possible!

IQVIA is a leading global provider of clinical research services, commercial insights and healthcare intelligence to the life sciences and healthcare industries. We create intelligent connections to accelerate the development and commercialization of innovative medical treatments to help improve patient outcomes and population health worldwide. Learn more at

IQVIA is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, status as a protected veteran, or any other status protected by applicable law.

IQVIA is committed to integrity in our hiring process and maintains a zero tolerance policy for candidate fraud. All information and credentials submitted in your application must be truthful and complete. Any false statements, misrepresentations, or material omissions during the recruitment process will result in immediate disqualification of your application, or termination of employment if discovered later, in accordance with applicable law.

We appreciate your honesty and professionalism.

The potential base pay range for this role, when annualized, is $89,000.00 - $. The actual base pay offered may vary based on a number of factors including job‑related qualifications such as knowledge, skills, education, and experience; location; and/or schedule (full or part‑time). Dependent on the position offered, incentive plans, bonuses, and/or other forms of compensation may be offered, in addition to a range of health and welfare and/or other benefits.

IQVIA is a leading global provider of clinical research services, commercial insights and healthcare intelligence to the life sciences and healthcare industries. We create connections that accelerate the development and commercialization of innovative medical treatments. Everything we do is part of a journey to improve patient outcomes and population health worldwide.

To get there, we seek out diverse talent with curious minds and a relentless commitment to innovation and impact. No matter your role, everyone at IQVIA contributes to our shared goal of helping customers improve the lives of patients everywhere. Thank you for your interest in growing your career with us.

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