Senior Director, Device Portfolio Insights

Location: Indianapolis

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism.

We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.
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* Position Summary:

** The Senior Director of Device Portfolio Insights serves as enterprise owner of device portfolio strategy, investment prioritization, and long-range value creation. This role orchestrates cross-functional integration across R&D, Clinical, Therapeutic Areas, Commercial, Finance, and Digital to drive portfolio decisions that maximize strategic and financial return.

This leader provides oversight of portfolio health, prioritization, and governance while ensuring integration between drug delivery devices and Lilly's clinical pipeline. Serving as the central hub for portfolio intelligence, this role drives resource allocation, investment optimization, and AI-enabled decision support. The position requires sophisticated analytical capabilities and the ability to synthesize complex information into actionable insights that guide executive decision-making.
** Responsibilities:
**** Strategic Mandate and Enterprise Ownership
*** Develop and maintain a comprehensive, integrated view of the device development portfolio spanning drug delivery pre-clinical & clinical research, device innovation, development, and commercialization projects, programs, and initiatives under device development
* Ensure seamless integration between drug delivery device development and Lilly's clinical molecule pipeline across all therapeutic areas
* Support annual portfolio strategic planning processes in collaboration with device development leadership
* Use market analysis, competitive intelligence, and technology assessments to inform portfolio strategy
* Identify whitespace opportunities and recommend new investment areas. Support build vs. buy vs. partner analyses for delivery system capabilities
** Cross‑Functional Orchestration
*** Leverage deep portfolio knowledge and financial expertise to optimize investment strategies at both project and portfolio levels
* Partner with Finance and PPM/CMC PM teams to develop accurate cost models, forecasts, and business cases for drug delivery system initiatives
* Track and report on portfolio expenditures, variance analysis, productivity, and return on investment metrics
* Support business case development for new initiatives and portfolio prioritization decisions
* Develop and update device development archetypes and support disease state benchmarking activities
** Decision-Focused Portfolio Intelligence
*** Develop, maintain, and continuously enhance the device development portfolio dashboard to support data-driven decision-making
* Establish key performance indicators (KPIs) and metrics that provide meaningful insights into portfolio health, progress, and value realization
* Create visualizations and reporting tools that enable leadership to quickly assess portfolio status, risks, and opportunities
* Implement predictive analytics and modeling capabilities to forecast portfolio outcomes
** Artificial Intelligence and Decision Science Leadership
*** Champion use of decision science, data science, and AI applications in device development business intelligence to improve portfolio operations
* Deploy predictive analytics and decision augmentation tools to enhance portfolio forecasting, risk assessment, scenario planning, and opportunity identification
* Identify resource constraints, bottlenecks, and capability gaps; recommend solutions
* Monitor resource utilization metrics and drive continuous improvement in capacity management
** Forward‑Looking Portfolio Deployment
*** Ensure clear and consistent communication of portfolio status, insights, and recommendations to device development leadership and cross-functional stakeholders
* Facilitate regular portfolio communication forums to share insights, trends, and priority shifts
* Identify, assess, and communicate portfolio-level risks, dependencies, and integration challenges. Develop risk mitigation strategies and contingency plans for high-impact portfolio risks
* Ensure transparent escalation of critical issues requiring leadership attention or intervention
* Build strong relationships with therapeutic area leaders, clinical development teams, and commercial stakeholders
* Translate complex portfolio data into compelling narratives for executive audiences
** Serve as Strategic Portfolio leader
*** Prepare portfolio materials for governance reviews, decision forums, and executive leadership meetings
* Ensure governance readiness by maintaining current, accurate data on milestones, deliverables, risks, and…