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Principal Scientist, In Vitro Metabolism

Job in Indianapolis, Hamilton County, Indiana, 46262, USA
Listing for: IQVIA LLC
Full Time position
Listed on 2026-02-19
Job specializations:
  • Research/Development
    Research Scientist, Clinical Research, Medical Science, Data Scientist
  • Healthcare
    Clinical Research, Medical Science, Data Scientist
Salary/Wage Range or Industry Benchmark: 125000 - 150000 USD Yearly USD 125000.00 150000.00 YEAR
Job Description & How to Apply Below
Position: Principal Scientist, In Vitro Metabolism (1805127)
Location: Indianapolis

Principal Scientist, In Vitro Metabolism (1805127) page is loaded## Principal Scientist, In Vitro Metabolism (1805127) locations:
Indianapolis, Indiana, United States of America time type:
Full time posted on:
Posted Todayjob requisition :
R1522886# We are seeking Principal Scientist, In Vitro Drug Metabolism to join IQVIA Laboratories  hire passionate innovators who drive healthcare forward through thoughtful and inclusive collaboration. If you want to discover a career with greater purpose, join us as we transform and accelerate research and development.##

Job Summary:

This role provides scientific leadership in complex in vitro drug metabolism method development and supports clients across the drug development lifecycle, including IND‑enabling studies. The Principal Scientist independently designs and executes assays, interprets data, and delivers high‑quality client-facing outputs.## What You’ll Be Doing:
* Design and execute complex in vitro drug metabolism studies, including CYP, UGT, AO, FMO, metabolic clearance, and protein binding assays
* Serve as Principal Investigator on client studies and ensure clear communication of progress and results
* Develop, implement, and optimize new in vitro methods for client programs
* Prepare technical summaries, study protocols, and high-quality reports suitable for regulatory submission
* Lead multiple technical projects while guiding junior scientists in daily laboratory activities##

What We Are Looking For :
* Bachelor’s degree in biology, chemistry, or related field with 7+ years of in vitro ADME experience; OR a Master’s with 4+ years; OR a recent Ph.D. with relevant in vitro metabolism training.
* Hands‑on experience with in vitro ADME assays, including CYP inhibition/induction/phenotyping and protein binding
* Industry experience within a pharmaceutical ADME group or a CRO supporting IND‑enabling studies
* Technical proficiency with in vitro method development and related analytical tools
* Other Equivalent combination of education, training, and experience may be accepted in lieu of degree## The Knowledge,

Skills and Abilities

Needed for This Role:
* Ability to independently manage multiple complex scientific projects
* Strong data analysis, interpretation, and scientific communication skills
* Proficiency with Microsoft Excel, scientific software, and electronic lab documentation systems##

What We Offer You:

We put our employees at the center of everything we do and are committed to providing them, and their families, with benefits that meet their diverse and changing needs. We invest in integrated benefits programs and resources to take care of our employees’ physical, mental and emotional, financial and social well-being so they can thrive at home and at work, at any stage of their well-being journey.

To learn more about our benefits, visit  you’re looking to unleash your potential, join IQVIA Laboratories to help make the extraordinary possible!

IQVIA is a leading global provider of clinical research services, commercial insights and healthcare intelligence to the life sciences and healthcare industries. We create intelligent connections to accelerate the development and commercialization of innovative medical treatments to help improve patient outcomes and population health worldwide. Learn more atIQVIA is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, status as a protected veteran, or any other status protected by applicable law.

IQVIA is committed to integrity in our hiring process and maintains a zero tolerance policy for candidate fraud. All information and credentials submitted in your application must be truthful and complete. Any false statements, misrepresentations, or material omissions during the recruitment process will result in immediate disqualification of your application, or termination of employment if discovered later, in accordance with applicable law.

We appreciate your honesty and professionalism.

The potential base pay range for this role, when annualized, is…
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