Principal Research Scientist

Location: Indianapolis

Principal Research Scientist page is loaded## Principal Research Scientist locations:
Indianapolis, INtime type:
Full time posted on:
Posted Todayjob requisition :
R0025248
** At Elanco (NYSE: ELAN) – it all starts with animals!
**** As a global leader in animal health, we are dedicated to innovation and delivering products and services to prevent and treat disease in farm animals and pets.*
* ** At Elanco, we are driven by our vision of Food and Companionship Enriching Life and our purpose – all to Go Beyond for Animals, Customers, Society and Our People.
**** At Elanco, we pride ourselves on fostering a diverse and inclusive work environment. We believe that diversity is the driving force behind innovation, creativity, and overall business success. Here, you’ll be part of a company that values and champions new ways of thinking, work with dynamic individuals, and acquire new skills and experiences that will propel your career to new heights.
**** Making animals’ lives better makes life better – join our team today!
**** Your Role:
**** Your Responsibilities:
*** Serve as the intellectual leader for the design and development of all critical protein and cell-based assays, providing strategic and technical guidance to project teams.
* Architect the end-to-end in vitro screening strategy for diverse projects, designing bespoke assays to probe mechanism-of-action (MOA), determine potency, and characterize cellular responses.
* Define and manage the strategic balance of assay development and execution between internal teams and external Contract Research Organizations (CROs).
* Drive scientific innovation by evaluating and implementing cutting-edge technologies and new methodologies (e.g., AI/ML applications) to advance our screening cascades.
* Lead, mentor, and guide a team of 3-5 scientists, fostering their career development and building a culture of scientific rigor, curiosity, and collaboration.
* Act as a key scientific liaison, collaborating closely with leaders in medicinal chemistry, protein engineering, immunology, and virology to drive projects forward.
** What You Need to Succeed (Minimum Qualifications):**
* *
* Education & Experience:

** Ph.D. in Cell Biology, Molecular Biology, Immunology, or a related discipline with 8+ years of relevant industry experience; OR an M.S. with 12+ years of extensive, relevant industry experience.
* ** Technical Expertise:
** Demonstrated expertise in developing a wide array of cell-based assays (e.g., signaling, reporter, cytotoxicity, proliferation, target engagement).
* ** Modality

Experience:

** Proven experience with
** small molecule
** drug discovery, plus expertise in at least one other modality (large molecules/biologics or vaccines).
* ** Scientific Leadership:
** A track record of identifying critical scientific problems and independently driving the development of solutions that advance portfolio projects, consistent with an R3 level scientist.
** What will give you a competitive edge (Preferred Qualifications):
*** Experience working across all three modalities: small molecules, large molecules, and vaccines.
* Experience translating novel technologies or methodologies (e.g., AI/ML, high-throughput screening) from human health or other fields into an animal health research environment.
* Direct experience with the transfer of methods and data between internal teams and external collaborators or CROs.
* Demonstrated ability to influence cross-functional teams and manage competing priorities through clear communication and strong collaborative skills.
* A deep understanding of pharmacology, immunology, and/or virology principles.
** Additional Information:**
* ** Travel:
** 5-10%
* *
* Location:

** Global Elanco Headquarters
- Indianapolis, IN
- Hybrid Work Environment
** Elanco Benefits and Perks:
** We offer a comprehensive benefits package focusing on financial, physical, and mental well-being while encouraging our employees to pursue our purpose! Some highlights include:
* Multiple relocation packages
* Two weeklong shutdowns (mid-summer and year-end) in the US (in addition to PTO)
* 8-week parental leave
* 9 Employee Resource Groups
* Annual bonus offering
* Flexible work…