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Senior Computational Chemist, Oligonucleotide Therapeutics

Job in Indianapolis, Hamilton County, Indiana, 46262, USA
Listing for: Xenon7
Full Time position
Listed on 2026-06-26
Job specializations:
  • Research/Development
    Research Scientist, Drug Discovery, Biomedical Science
Job Description & How to Apply Below
Location: Indianapolis

A leading healthcare research organization in Indianapolis is seeking a highly motivated computational chemist to apply physics-based modeling and cheminformatics in the design of chemically modified oligonucleotide therapeutics. Responsibilities include performing molecular dynamics simulations, applying free energy methods to predict binding affinities, and collaborating with medicinal chemists. A PhD in a relevant field is required, along with expertise in molecular dynamics and cheminformatics tools.

Strong programming skills in Python are essential, and familiarity with machine learning is preferred.
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Position Requirements
10+ Years work experience
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