Post Doctoral Scientist - Molecular Pharmacology

Post-Doctoral Scientist – Molecular Pharmacology

Are you looking to make an impact in drug discovery at the frontier of G-protein coupled receptor (GPCR) science? We are seeking an ambitious post-doctoral scientist with strong research and communication skills to contribute to a high-visibility research program in quantitative GPCR pharmacology.

• Conduct innovative molecular pharmacology studies to characterize the mechanisms of action of GPCR ligands across multiple receptor systems of therapeutic relevance.
• Work with and be mentored by industry-leading molecular pharmacologists, structural biologists, computational scientists, and medicinal chemists.
• Present findings at internal and external scientific meetings and publish extensively in high-quality peer‑reviewed journals.

• PhD in pharmacology, biochemistry, biophysics, molecular biology, or a closely related life science discipline (all completed requirements by October 2026).
• Qualified applicants must be authorized to work in the United States on a full‑time basis. Lilly will not provide support for or sponsor work authorization or visas for this role.

• Training or background in membrane receptor biology, receptor pharmacology, signal transduction, or quantitative pharmacology would be advantageous.
• Self-directed and highly motivated, with a commitment to pursuing both technical excellence and publication goals.
• Excellent communicator (oral and written) with a strong or developing publication record.
• Proficient in data analysis, graphing, and scientific reporting (Graph Pad Prism, Python, Excel, PyMOL, MOE).
• Experience with ligand binding techniques (competition, saturation, kinetic assays) in live cell or membrane formats.
• Experience with cell-based GPCR signaling assays, including cAMP, IP1, β‑arrestin recruitment, intracellular calcium measurement, or phosphoprotein measurement.
• Familiarity with quantitative pharmacological modelling or kinetic simulation approaches.
• Experience with mammalian cell culture and standard molecular biology techniques.
• Understanding or practical experience of modern structural and computational biology approaches.
• Interest in the mechanistic and theoretical foundations of receptor pharmacology.

• This is an onsite position based in Indianapolis, Indiana.
• This position is not permanent. It is a fixed‑term position up to 2 years with a possible 2‑year extension.

Postdoctoral scientists help us continue this pursuit. During your experience you will receive top industry research experience in a world‑class molecular pharmacology environment, mentoring by some of Lilly’s leading scientists in GPCR biology, structural pharmacology, and quantitative modelling, laboratory and professional training to further your scientific and career development, and collaboration and networking across a vibrant community of postdoctoral scientists and research colleagues.

Actual compensation will depend on a candidate’s education, experience, skills, and geographic location. The anticipated wage for this position is $58,000 – $123,200. Full‑time equivalent employees will also be eligible for a company bonus (depending, in part, on company and individual performance). Lilly offers a comprehensive benefit program, including eligibility to participate in a company‑sponsored 401(k); pension; vacation benefits; medical, dental, vision and prescription drug benefits;

flexible benefits (e.g., healthcare and/or dependent day‑care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well‑being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).

Lilly is a proud EEO employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.