Researcher, Peptide Chemistry

The Opportunity:

The Researcher in Peptide Chemistry will support internal portfolio projects and external collaborative research activities through the synthesis, purification, and characterization of peptides. This laboratory-focused role includes maintaining instrumentation and reagent inventory, organizing and storing experimental data, and communicating results to relevant project teams. The position offers the opportunity for a candidate passionate about peptide synthesis to contribute directly to impactful drug discovery research while supporting high-quality laboratory operations, reliable documentation, and effective project execution.

• Peptide Synthesis, Purification, and Characterization
• Synthesize, purify, and characterize peptides in support of internal portfolio projects and sponsored research activities.
• Execute peptide chemistry workflows with attention to quality, reproducibility, and project timelines.
• Analyze and summarize peptide characterization data to support research decision-making.

• Maintain laboratory instrumentation to support ongoing peptide chemistry activities.
• Monitor, organize, and maintain reagent inventory to ensure materials are available for project needs.
• Coordinate routine laboratory upkeep and communicate maintenance or supply needs as appropriate.

• Organize, store, and maintain experimental data and documentation in accordance with project and laboratory expectations.
• Communicate data, results, and project updates to relevant project teams in a clear and timely manner.
• Support effective collaboration by ensuring accurate records and accessible data for internal stakeholders.

• Bachelor’s degree in chemistry, biochemistry, chemical biology, pharmaceutical sciences, or a related field is required. Relevant experience may be considered in lieu of degree requirements.
• At least 3 years of laboratory experience with automated and manual solid-phase peptide synthesis, purification, and/or characterization techniques.
• Familiarity with HPLC purification and LC-MS analysis of synthetic peptides.
• Ability to maintain accurate experimental records and organize data in a clear, accessible manner.
• Experience with solid-phase peptide synthesis is highly.
• Experience with preparative or analytical HPLC purification workflows.
• Experience with peptide characterization using LC-MS, MS, or related analytical platforms.
• Ability to support laboratory operations, including instrumentation upkeep and reagent inventory management.
• Exceptional organizational, communication, and collaboration skills.
• Willingness to learn new techniques and support evolving project needs is essential.
• Proficiency in Microsoft Office Suite.

• Experience with native chemical ligation protocols.
• Experience with formulation of peptide drugs.
• Experience maintaining laboratory instrumentation, reagent inventory, and organized data storage systems.
• Experience supporting drug discovery research, collaborative research programs, and/or cross-functional project teams

Competitive salary and comprehensive benefits offered commensurate with experience.

The Indiana Biosciences Research Institute (IBRI) is a first-in-class translational medicine institute dedicated to advancing life sciences in the race to eliminate disease and improve human health and life.

By connecting early-stage biotech companies with cutting-edge life science discoveries
-and backed by the mission and resources of industry leaders, investors, and philanthropic partners-IBRI is successfully evolving a new, independent model to conquer disease, uniting previously fragmented forces in the quest for cures.

Carefully curating and supporting early-stage companies with investment, talent, and space, IBRI strategically accelerates drug discovery. Our work benefits from the relatively low cost of living and doing business here, allowing more resources to be directed toward science.

Fueled by the same entrepreneurial creativity as the groundbreaking scientific work we support, IBRI’s labs advance research across the…