Senior Associate Scientist , Isotope Production

Summary

At Rayze Bio, every day is an opportunity to ignite meaningful change. As a wholly-owned subsidiary of Bristol Myers Squibb, Rayze Bio blends the nimble, pioneering spirit of an emergent biotech with the global expertise and resources of a leading innovator in oncology. Our mission is to develop transformative radiopharmaceutical therapies that offer new hope for patients living with cancer. Here, you’ll join a multidisciplinary team where your ideas are valued, your expertise is amplified, and collaboration is at the heart of everything we do.

From day one, expect to make an immediate impact, on our science, on our teams, and most importantly, on patients. Learn more about Rayze Bio:

• Participate in the experimental design for R&D radio chemical processes associated with the production, purification, and recovery of Actinium-225 and related isotopes, under the direction of senior scientists.
• Execute the implementation of separation and purification methods using chromatography, precipitation, solvent extraction, and other radio chemical techniques.
• Run process scale-up studies, transitioning from benchtop to process scale operations for shielded hot cell operations.
• Perform hands‑on laboratory work with radioactive materials, including alpha‑emitting isotopes, following established radiological safety practices and procedures.
• Help maintain process flow diagrams, equipment logs, standard operating procedures, and technical documentation.
• Collaborate with engineering and scientific staff on process equipment setup, automation systems, and routine facility operations.
• Independently execute target processing activities, radionuclide recovery tasks, waste handling, and basic process troubleshooting.
• Assist with literature review and data gathering to support process improvement efforts.
• Collect, organize, and perform basic analysis of experimental data using standard scientific methods, under supervision.
• Support technology transfer activities by assisting with documentation and execution of transfer protocols.
• Work with external vendors and business partners to install and maintain laboratory equipment.
• Follow established procedures with attention to detail and contribute to a culture of scientific rigor and operational excellence.
• Less than 5% of travel may be required.

• BS/MS in Radiochemistry, Chemistry, or a related scientific field, with 2+ years of direct experience with radioactive materials.
• Additional cGMP and chemistry laboratory experience is preferred.

• Coursework or laboratory exposure to Actinium-225, Radium-226, Thorium-229, Thorium-228, Radium-224, or other alpha‑emitting isotope systems is a plus.
• Willingness to work with hot cells, glove boxes, shielded enclosures, and remote handling systems.
• Basic familiarity with cyclotron‑produced radioisotopes and post‑irradiation target processing is preferred.
• Prior experience with ion exchange chromatography, extraction chromatography, solvent extraction, or radionuclide recovery methods, analytical instrumentation such as HPGe spectroscopy, alpha spectroscopy, ICP-OES, ICP-MS, liquid scintillation counting, or related techniques is preferred.
• Strong attention to detail with good data documentation and technical writing skills.
• Strong professional ethics, integrity, and ability to maintain confidential information.
• Uses AI tools to enhance individual productivity and quality of work

Physical Demands

While performing the duties of this job, the employee is regularly required to sit, reach with hands and arms, and talk or hear. The employee must occasionally lift and/or move up to 30 pounds. Specific vision abilities required by this job include close vision and distance vision.

This is a position that requires working in a laboratory environment, protective clothing, gloves, and safety glasses are required while working in a laboratory environment with radioactive materials.

The noise level in the work environment is usually moderate.

Indianapolis - Rayze Bio - IN: $82,236 - $99,650

The starting compensation range(s) for this role are listed above for…