Sr Principal Chemist- Product Protection

Organization/Position Overview

The Sr. Principal Chemist is a member of the AQCO’s Analytical Sciences Team and will conduct non‑routine analyses of drug substances, drug products, and other non‑typical samples suspected of counterfeiting, tampering, or diversion. Samples may originate from product complaints, proactive surveillance, or global law enforcement agencies. The role supports advanced authentication strategies for pipeline assets and expands capacity for increased anti‑obesity medication sample volumes.

• Perform analyses of suspect products using LC‑MS, HPLC, UPLC, spectroscopy, and other analytical techniques.
• Analyze LC‑MS data and perform limited structure elucidation on both small and large molecules.
• Provide non‑laboratory support for other product authentication processes (e.g., packaging authentication, variable data verification).
• Collaborate with AQCO colleagues and other analytical SMEs to solve complex sample analyses.
• Support special studies proposed by business partners (e.g., Global Security, Legal).
• Develop and validate robust, scientifically advanced methods with the required performance attributes to satisfy stakeholder needs.
• Actively participate in the mass spectrometry community/forum to maintain proficiency and expertise.
• Troubleshoot issues with methods and/or equipment.
• Execute testing protocols in accordance with local procedure and regulatory requirements.
• Provide training or mentorship to other AQCO colleagues or cross‑functional team members as required.

• Deep technical expertise in separation sciences, spectroscopy, hyphenated mass spectrometry techniques (MS and MSn) and their application.
• Demonstrated proficiency in the use of multiple instrument platforms (Thermo, Agilent, Waters, etc.) and associated software platforms (Chromeleon, Excalibur, Biopharma Finder, Genedata, etc.).
• Ability to handle controlled substances.
• Ability to work with non‑technical personnel.
• Ability to manage and communicate confidential information.
• Strong technical problem‑solving ability both independently and as part of a team.
• Motivated to work independently to produce high quality work product efficiently.
• High attention to detail in all aspects of the work.
• Basic requirements:
  Minimum B.S. in Chemistry or related scientific field; 5+ years of recent bench experience in a laboratory environment.

• Ability to perform structure elucidation on both small and large molecules.
• Knowledge of Lilly systems such as NuGenesis (eLN), Quality Docs, SAP, Smart Lab, etc.
• Strong written and oral communication skills.
• Ability to work independently, self‑sufficiently, and proactively in the performance of work duties.
• Ability to resolve conflict and promote good decision making among team members.
• High learning agility and flexibility to achieve required outcomes.
• Working knowledge in one or more of the following: chemical, peptide or protein synthesis.
• Familiarity and experience with spectroscopic techniques (e.g., FTIR, NIR, Raman).
• Imaginative approach to problem solving and solution discovery.

Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.

Anticipated wage range: $65,250 – $169,400 full‑time; eligible for a company‑sponsored bonus. Lilly offers a comprehensive benefit program that includes 401(k), pension, vacation, medical, dental, vision, prescription drug, flexible spending accounts, life insurance, and well‑being benefits.