Director, Analytical Chemistry Extended Characterization

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism.

We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world.

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism.

We give our best effort to our work, and we put people first. We're looking for motivated individuals who are determined to make life better for people around the world.

Verve Therapeutics is a wholly owned subsidiary of Lilly. Verve is a biotechnology company created with a singular focus: to protect the world from heart disease. Founded by world-leading experts in cardiovascular medicine, human genetics and gene-editing, the company aims to develop transformative, once-and-done therapies for coronary heart disease. Verve's gene editing medicines are designed to safely edit the genome of adults and mimic naturally occurring gene variants to permanently lower LDL cholesterol and triglyceride levels.

This is a rare and exciting opportunity to build something from the ground up. We are seeking a Director, Analytical Development to serve as a leader within Verve's Analytical Development function. This is not a role where you inherit a team and maintain the status quo - you will recruit, shape, and lead a team of scientists and associates, building the analytical capabilities that will power Verve's late-stage pipeline from the inside out.

You will architect and implement next-generation analytical methods for the extended characterization of RNA drug substances (gRNA and mRNA) and LNP drug products, driving programs from development through commercialization.

You'll operate at the intersection of science and strategy, working hand-in-hand with cross-functional teams across Lilly's Product Research & Development (PRD) organization - leveraging world-class resources and expertise to accelerate Verve's programs. Your team will also support non-GMP testing across development studies including comparability assessments, process development, stability, and product and process characterization. As part of Verve's Technical Operations team, you will be a key partner to Quality Control, Quality Assurance, Process Development, and Analytical Research & Development - with real influence over how this function is built and where it goes.

If you're a scientifically driven leader who thrives on building, solving hard problems, and making a meaningful impact on human health, this is the role for you!

** Responsibilities:*
* + Lead a team of scientists working on mRNA, gRNA and LNP assays focused on biophysical extended characterization.

+ Partner across the Analytical Development team and cross-functionally with  &D and SMDD to lead, plan, and execute complex characterization studies; serve as the analytical lead in cross-functional interactions.

+ Develop and implement methods intended for product characterization to support late stage and commercialization of gene editing programs.

+ Provide technical expertise for the structural characterization of gRNAs, mRNAs and lipid nanoparticle (LNP) complexes.

+ Serve as analytical lead for CMC project teams and other VPT teams.

+ Oversee troubleshooting, tech transfer, and phase-appropriate GMP validation of analytical methods at the internal Quality Control lab and at contract testing labs in collaboration with Quality team.

+ Author and review technical reports and regulatory submissions.

+ Provide guidance and support to team members, promoting…