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Director, Engineering and Maintenance

Job in Irvine, Orange County, California, 92713, USA
Listing for: Initial Therapeutics, Inc.
Full Time position
Listed on 2026-05-16
Job specializations:
  • Engineering
    Operations Manager, Manufacturing Engineer, Process Engineer
Salary/Wage Range or Industry Benchmark: 180000 - 280000 USD Yearly USD 180000.00 280000.00 YEAR
Job Description & How to Apply Below

"Expect to grow", personally and professionally:
At Siegfried, we offer exciting challenges and ample opportunities to showcase your talents. As a trusted and respected partner to the pharmaceutical industry, we uphold the highest standards in safety, quality and sustainability, while fostering a culture that empowers you to thrive. Join a rapidly expanding global company, where diverse perspectives and experiences come together in a collaborative environment. Here, you'll find a workplace that values both collective success and your individual contributions—offering long‑term opportunities to grow and make an impact.

Your

Role:

We are seeking a Director of Engineering & Maintenance to lead critical site functions, drive strategic initiatives, and elevate operational excellence across our pharmaceutical manufacturing operations. This is a leadership role where technical expertise meets strategic vision. As a key member of the Site Leadership Team (SLT), you will play a pivotal role in shaping the future of our site through engineering innovation, capital project execution, and people development.

Your Profile:

As Director of Engineering & Maintenance, you will:

  • Define and execute the mid and long term engineering strategy aligned with site and corporate goals
  • Lead major CAPEX projects from concept through execution—ensuring delivery on time, within budget, and to specification
  • Establish and drive robust governance processes to track and improve operational performance
  • Oversee Engineering, Maintenance, Facilities, Automation, and Calibration teams
  • Ensure equipment reliability, asset lifecycle optimization, and KPI performance
  • Partner cross‑functionally with Manufacturing, M&ST, Quality Assurance, and Project Management
  • Support facility expansions, equipment acquisitions, and site modifications, including qualification activities
  • Drive continuous improvement in aseptic operations, clean utilities, and GMP compliance
  • Lead technical evaluations, equipment selection, and implementation of advanced manufacturing technologies
  • Actively contribute to Deviation, CAPA, and Change Control (DCR) processes
  • Manage departmental budgets, including CAPEX and maintenance budgets exceeding $3M
  • Develop and mentor a high‑performing engineering organization
What You Bring
  • Strong leadership presence with the ability to inspire, develop, and lead technical teams
  • Deep expertise across:
    • Pharmaceutical engineering & manufacturing
    • Maintenance & reliability systems
    • Automation & process equipment
    • GMP compliance and aseptic operations
  • Proven ability to manage complex capital projects and cross‑functional initiatives
  • Excellent communication skills with the ability to influence at all levels
  • Strong analytical mindset with sound decision‑making capabilities
  • Proficiency with tools such as AutoCAD, Solid Works, Microsoft Project, Excel, and related systems
Required Experience & Education
  • Bachelor’s Degree in Engineering (or equivalent)
  • 15+ years of engineering experience in the pharmaceutical industry
  • 7+ years leading engineering, maintenance, and facilities teams
  • 5+ years of GMP experience, including aseptic processes and clean utilities

Demonstrated ownership of CAPEX and maintenance budgets > $3M

Your Benefits:
  • Medical, dental, and vision coverage (including dependents)
  • Life insurance, short and long term disability
  • Flexible Spending Accounts (FSA) & Health Savings Accounts (HSA)
  • 401(k) with company match
  • Generous Paid Time Off (PTO)

Target Base Salary: $180,000 – $280,000

Individual compensation packages are based on various factors unique to each candidate, including skill set, experience, qualifications and other job‑related reasons.

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