NPI & LCM Principal Engineer | Irvine, CA

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and Med Tech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity.

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As guided by Our Credo, Johnson & Johnson is responsible to our employees who work with us throughout the world. We provide an inclusive work environment where each person is considered as an individual. At Johnson & Johnson, we respect the diversity and dignity of our employees and recognize their merit.

Supply Chain Engineering

Process Engineering

Scientific/Technology

Irvine, California, United States of America

Fueled by innovation at the intersection of biology and technology, we’re developing the next generation of smarter, less invasive, more personalized treatments. As Johnson & Johnson Med Tech Electrophysiology, we have one goal – to ensure those with atrial fibrillation can live the lives they want. For more than 30 years, we’ve been the global market leader in the science and technology of cardiac arrythmia treatment.

Our suite of tools means electrophysiologists are empowered to personalize their approaches for patients with effective and reproducible workflows. Together, we’re changing what it means to be diagnosed with atrial fibrillation or other cardiac arrhythmias. Your unique talents will help patients on their journey to wellness. Learn more at

The NPI & LCM Principal Engineer provides strategic technical leadership across new product development, design transfer, commercialization, and lifecycle management, serving as the primary engineering liaison between R&D and Supply Chain. Working with significant autonomy, this role directs cross-functional engineering teams to deliver safe, compliant, manufacturable, reliable, and cost-effective products that achieve quality, yield, capability, and delivery objectives. The Principal Engineer defines technical direction, project scope, equipment needs, resources, and schedules;

leads design and process changes; and develops the specifications, work instructions, validation protocols, reports, and controlled documentation required for successful execution and compliance. As a technical authority, the role supervises and coordinates engineers and technicians, mentors junior engineers, and drives effective decisions that strengthen product quality, operational performance, and long-term business value. The role converts product and process requirements into scalable manufacturing solutions by leading design for manufacturability, product and process characterization, tooling and equipment development, production test methods, and qualification and validation activities, including IQ, OQ, PQ, and APQ.

It applies advanced engineering principles and Process Excellence methods to optimize yield, resolve complex mechanical and electrical assembly challenges, and sustain manufacturing performance.

• Lead cost-reduction initiatives for products, materials, and manufacturing techniques using engineering and financial analysis.
• Independently resolve complex engineering challenges and represent the organization in technical discussions.
• Apply advanced…