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Clinical Nurse III - Hematology; 7th Floor - Nights

Job in Irvine, Orange County, California, 92713, USA
Listing for: City of Hope
Full Time position
Listed on 2026-05-19
Job specializations:
  • Nursing
    Oncology Nurse, Clinical Nurse Specialist, RN Nurse, Healthcare Nursing
Salary/Wage Range or Industry Benchmark: 80000 - 100000 USD Yearly USD 80000.00 100000.00 YEAR
Job Description & How to Apply Below
Position: Clinical Nurse III - Hematology (7th Floor) - Nights

City of Hope Orange County is transforming cancer treatment by bringing world‑class expertise and specialized care closer to home. Supported by a regional network of care, our 11‑acre academic cancer campus in Irvine is home to City of Hope Orange County Lennar Foundation Cancer Center, our outpatient cancer center, and Orange County’s only cancer specialty hospital.

With the opening of the hospital, the full continuum of advanced cancer care—from prevention through survivorship—will be available in Orange County for the first time, eliminating the need to travel for lifesaving treatment. Seamlessly connected to our outpatient cancer center, the new clinical research hospital will feature 73 inpatient beds, advanced surgical suites, groundbreaking clinical trials, and holistic services such as rehabilitative therapy and spiritual care.

This isn’t standard cancer care. This is lifesaving cancer care. This is Hope.

Position Summary

The Hematology unit provides comprehensive care to patients with hematologic malignancies such as leukemia, lymphoma, and multiple myeloma. In addition, the unit also specializes in managing patients undergoing CAR T therapy and those participating in clinical research trials. The unit is equipped to diagnose, treat, and manage various blood‑related cancers through a multidisciplinary approach. This opportunity is for full‑time, 12‑hour shifts (3 shifts per week) and is designated for the night shift.

This position is eligible for a night shift differential up to $6.50/hr and weekend differential up to $15.60/hr.

As a successful candidate, you will:
  • Patient Assessment and Monitoring: conduct thorough assessments of patients with hematologic malignancies, including physical exams, review of medical history, and assessment of symptoms such as fatigue, bruising, and bleeding. Monitor vital signs, laboratory results, and response to treatment to detect any changes in patient status.
  • Chemotherapy Administration: administer chemotherapy and other systemic treatments according to established protocols and guidelines. Ensure accurate dosing, monitor for potential side effects, and provide supportive care to minimize treatment‑related complications.
  • Symptom Management: assess and manage symptoms associated with hematologic malignancies and their treatments, such as pain, nausea, anemia, and neutropenia. Administer medications, provide comfort measures, and educate patients on self‑care techniques to improve symptom control and quality of life.
  • Patient

    Education:

    play a crucial role in educating patients and their families about their diagnosis, treatment options, and potential side effects. Provide information on managing treatment‑related symptoms, adhering to medication regimens, and accessing support services such as counseling, nutrition therapy, and financial assistance.
  • Care Coordination: collaborate with the multidisciplinary team to develop and implement individualized care plans for patients with hematologic malignancies. Coordinate appointments, diagnostic tests, and consultations with specialists to ensure seamless continuity of care throughout the treatment process.
Your qualifications should include:
  • Bachelor’s or Master’s degree in Nursing is required
  • Current California RN license
  • Minimum of three (3) years related experience
  • Basic Life Support (BLS) CPR Card through American Heart Association
  • Advanced Cardiac Life Support (ACLS) Card through American Heart Association
  • Preferred experience:

    Oncology, Hematology, Intensive Care (ICU), Step Down (SDU)

City of Hope employees pay is based on the following criteria: work experience, qualifications, and work location.

City of Hope is an equal opportunity employer.

To learn more about our Comprehensive Benefits, please

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