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Scientist l, Biological Research

Job in Irvine, Orange County, California, 92713, USA
Listing for: AbbVie
Full Time position
Listed on 2026-06-26
Job specializations:
  • Research/Development
    Research Scientist
Job Description & How to Apply Below

Job Description

The Toxin Innovation Group is seeking a highly motivated Scientist I to contribute to the design, execution, and communication of novel research within a highly collaborative neurotoxin discovery and innovation program. The successful candidate will work on a variety of cell‑based assays to evaluate protein‑based therapeutics and contribute to their pharmacological characterization. Expertise in maintaining induced pluripotent stem cell (iPSC) cultures and executing complex cell‑based assays is required.

While taking personal responsibility for the success of assigned tasks and projects, the successful candidate will collaborate extensively with other scientists.

This position requires work with select agents and toxins (i.e., Biosafety Level 2 laboratories). Access to and use of select agents is regulated by federal policies; therefore, the candidate must conduct all work activities in compliance with Abb Vie internal requirements and applicable regulatory requirements.

Key Responsibilities
  • Culture cells in a sterile environment, including the expansion, differentiation, and maturation of human iPSC‑derived neurons.
  • Independently design and execute in vitro pharmacological studies; implement or innovate new experimental protocols as needed.
  • Perform in‑depth data analysis, draw conclusions, and present findings to multidisciplinary teams.
  • Demonstrate critical thinking to troubleshoot and provide creative solutions to experimental challenges.
  • Collaborate with cross‑functional team members to achieve organizational goals, ensuring excellence in execution and effective workload prioritization.
Qualifications
  • Highly motivated, hands‑on experimentalist who thrives in a collaborative, multidisciplinary environment.
  • Demonstrates flexibility and a commitment to scientific excellence.
  • Possesses strong interpersonal and organizational skills, as well as creative thinking ability.
  • Able to perform experiments independently and work effectively in a team environment.
  • Interprets results and draws conclusions from multi‑step experiments; notes significant deviations, uses scientific literature to suggest, design, and pursue relevant experiments.
  • Demonstrates meticulous attention to detail and diligence in record keeping.
Education and Experience
  • Minimum of a bachelor’s degree in a biological science field with 5 years of experience in an academic or industry laboratory setting.
  • Expertise in aseptic techniques, including maintaining iPSC cell cultures is required.
  • Experience in cell transfection/transduction is preferred.
  • Expertise in executing enzyme‑linked immunosorbent assays (ELISA), complex cell‑based assays, and western blotting is required.
  • Experience with immunohistochemistry, microscopy techniques, and/or flow cytometry is preferred.
  • Computer skills: working knowledge of MS Office (Excel, Word, PowerPoint) is required.
  • Knowledge of graphing software (e.g., Graph Pad Prism) and a basic understanding of statistical analyses are preferred.
  • Strong writing and communication skills.
Benefits
  • Compensation is based on the company’s pay scale and may vary with geographic location. The range may be modified in the future.
  • Comprehensive benefits package including paid time off (vacation, holidays, sick leave), medical/dental/vision insurance, and a 401(k) plan for eligible employees.
  • Eligibility to participate in short‑term incentive programs.
Equal Opportunity

Abb Vie is an equal‑opportunity employer and is committed to operating with integrity, driving innovation, and serving our community. Equal Opportunity Employer/Veterans/Disabled. Applicants seeking a reasonable accommodation can find information at

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