Principal Enterprise Architect, Digital Solutions

McKesson is an impact-driven, Fortune 10 company that touches virtually every aspect of healthcare. We are known for delivering insights, products, and services that make quality care more accessible and affordable. Here, we focus on the health, happiness, and well‑being of you and those we serve – we care.

What you do at McKesson matters. We foster a culture where you can grow, make an impact, and are empowered to bring new ideas. Together, we thrive as we shape the future of health for patients, our communities, and our people. If you want to be part of tomorrow’s health today, we want to hear from you.

The Principal Enterprise Architect, Digital Solutions is a senior leader responsible for defining and advancing the enterprise digital architecture strategy that enables scalable, secure, and innovative digital solutions for US Oncology Practices. This role partners closely with executive leaders, business stakeholders, clinical teams, and technology teams to translate Practice strategy into cohesive architectural direction.

• Unified enterprise architecture blueprint established and regularly updated as needed.
• Multi-year digital roadmap delivered and socialized, with regular updates as needed.
• Architecture governance adopted across teams.
• Modernization and interoperability improvements realized.

• Define and evolve the enterprise digital architecture vision, principles, and roadmaps aligned with business objectives.
• Provide architectural leadership for major digital initiatives, platform strategies, and transformation programs.
• Advise executives and senior leaders on technology trends, risks, and long-term architectural implications.
• Ensure digital solutions are secure, scalable, interoperable, and compliant with enterprise and regulatory standards.
• Establish and maintain reference architectures, patterns, and governance.
• Influence and mentor architects and technical leaders through thought leadership.

• Enterprise-wide scope with significant strategic and technical influence.
• Operates effectively in highly complex and ambiguous environments.
• Combines deep technical expertise with business and strategic acumen.
• Recognized authority for digital architecture and cross-domain design decisions.

• Degree or equivalent and typically requires 13+ years, with 8+ years of direct work related experience. Less years required if has relevant Master’s or Doctorate qualifications.

• Extensive experience in enterprise architecture or engineering leadership roles.
• Expertise in cloud modernization, multi-tenant platforms, and large-scale system design.
• Strong integration architecture background with APIs and interoperability standards.
• Experience with data platforms, semantic layers, analytics, and governed access models.
• Familiarity with clinical systems and oncology digital workflows preferred.

• Experience in oncology, clinical operations, or life sciences.
• Certifications:
  
  TOGAF, AWS/Azure Architect.
• Experience applying AI/ML to enterprise digital solutions, defining AI platform standards, and familiarity with cloud‑native AI services.

• Up to 25% travel.

We are proud to offer a competitive compensation package at McKesson as part of our Total Rewards. The pay range shown below is aligned with McKesson's pay philosophy, and pay will always be compliant with any applicable regulations. In addition to base pay, other compensation, such as an annual bonus or long‑term incentive opportunities, may be offered. For more information regarding benefits at McKesson, please .

Our Base Pay Range for this position
$178,800 - $298,000

McKesson is an Equal Opportunity Employer. McKesson provides equal employment opportunities to applicants and employees, without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability, age, genetic information, or any other legally protected category. For additional information on McKesson’s full Equal Employment Opportunity policies, visit our Equal Employment…