Principal Enterprise Architect - Enterprise Applications
Listed on 2026-08-02
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IT/Tech
Cloud Computing: Infrastructure & Operations, IT Consultant, IT Project Manager, Systems Engineer
McKesson is an impact-driven, Fortune 10 company that touches virtually every aspect of healthcare. We are known for delivering insights, products, and services that make quality care more accessible and affordable. Here, we focus on the health, happiness, and well-being of you and those we serve – we care. What you do at McKesson matters. We foster a culture where you can grow, make an impact, and are empowered to bring new ideas.
Together, we thrive as we shape the future of health for patients, our communities, and our people. If you want to be part of tomorrow’s health today, we want to hear from you.
The Principal Enterprise Architect - Enterprise Applications will play a critical role in defining and governing enterprise application architecture strategies that support McKesson’s business objectives. This individual will partner closely with business leaders, product teams, engineering teams, and enterprise architects to ensure scalable, secure, and integrated solutions across Supply Chain, Finance, HR, CRM, and other enterprise platforms. The ideal candidate will have extensive experience leading complex enterprise application transformations, establishing architecture standards, and guiding technology investment decisions across large-scale organizations.
Key Responsibilities- Enterprise Architecture Leadership:
Represent the Enterprise Applications organization within the Enterprise Architecture Council and other governance forums. - Define, maintain, and enforce architectural standards, principles, reference architectures, and best practices across Enterprise Applications.
- Lead cross-functional architecture reviews and design decisions to ensure scalable, secure, and maintainable solutions.
- Develop target-state architectures and technology roadmaps supporting business and digital transformation initiatives.
- Collaborate with business stakeholders and technology leaders to align enterprise application strategies with organizational goals.
- Provide architectural leadership for modernization, cloud adoption, AI-enabled automation, platform consolidation, and SaaS transformation initiatives.
- Ensure effective integration and interoperability across enterprise platforms and business capabilities.
- Evaluate emerging technologies and provide recommendations that improve business outcomes, operational efficiency, and customer experience.
- Lead architecture across Enterprise Application domains including:
Supply Chain, Finance, Human Resources, Customer Relationship Management (CRM), Procurement and Contract Lifecycle Management. - Design and govern cross-platform integrations among enterprise systems including: SAP, Workday, Service Now, Salesforce, People Soft, Contract Lifecycle Management solutions.
- Establish architecture patterns, integration frameworks, API strategies, and data exchange standards.
- Ensure enterprise applications support scalability, resilience, performance, compliance, and security requirements.
- Lead business capability mapping and end-to-end process architecture initiatives across multiple functional domains.
- Partner with business and technology teams to define strategic technology roadmaps and investment priorities.
- Provide architecture oversight for key transformation programs, cloud migrations, ERP initiatives, platform upgrades, and modernization efforts.
- Support portfolio prioritization through architecture assessments, technology rationalization, and solution evaluation.
- Establish architectural governance processes to ensure projects align with enterprise standards and strategic objectives.
- Drive adoption of enterprise architecture methodologies, tools, and model-based architecture practices.
- Serve as a trusted advisor to senior leadership and executive stakeholders.
- Present architecture strategies, technology recommendations, and investment proposals to executive leadership teams.
- Facilitate decision-making among technical and business stakeholders to balance risk, cost, complexity, and business…
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