Postdoctoral Researcher position in the Laboratory of Cellular Proteostasis

International Institute of Molecular and Cell Biology in Warsaw

Organisation/Company International Institute of Molecular and Cell Biology in Warsaw Research Field Biological sciences » Biology Researcher Profile Established Researcher (R3) Positions Postdoc Positions Final date to receive applications 16 Aug 2026 - 23:59 (Europe/Warsaw) Country Poland Type of Contract Permanent Job Status Full-time Hours Per Week 40 Offer Starting Date 1 Sep 2026 Is the job funded through the EU Research Framework Programme?

Other EU programme Reference Number 2025/58/E/NZ3/00511 Is the Job related to staff position within a Research Infrastructure? No

The
Laboratory of Cellular Proteostasis at the International Institute of Molecular and Cell Biology (IIMCB), Warsaw led by Dr. Lidia Wrobel is seeking ahighly motivated, creative, and independent Postdoctoral Researcher to join our team.

You will join the project entitled “ Subcellular localization and function of the ubiquitin–proteasome system in aging and neurodegeneration ” carried out as the SONATA BIS grant no 2025/58/E/NZ3/00511 of the National Science Centre, Poland led by Dr. Lidia Wrobel.

As a Postdoctoral Researcher in our group, you will be responsible for the development and implementation of state‑of‑the‑art human neuronal models of ageing and neurodegeneration
, using induced pluripotent stem cells (iPSCs) and patient‑derived fibroblasts
. Your research will focus on understanding how the Ubiquitin–Proteasome System changes during neuronal ageing and in neurodegenerative diseases.

You will apply genome‑wide CRISPR‑Cas9 screening approaches to identify novel regulators of proteasome activity and investigate how modulation of these factors can restore proteasome function in ageing and diseased neurons. The ultimate goal of this work is to uncover new therapeutic strategies for neurodegenerative disorders
.

The position offers the opportunity to work at the interface of stem cell biology, functional genomics, and neurodegeneration research
, within a multidisciplinary and collaborative research environment.

The ideal candidate should be able to pursue challenging tasks and achieve objectives and collaborate with other researchers.

Candidates will be selected in an open competition, according to the procedure complying with the rules of the European Charter for Researchers and the Code of Conduct for the Recruitment of Researchers as a part of HR Excellence in Research strategy.

• Holds PhDin molecular biology, biochemistry, biophysics, or a related field (completed or expected soon).
• The candidate must meet the eligibility conditions set by the National Science Centre (NCN) for persons employed in a post‑doc type position. In particular, the person employed in this position obtained their PhD degree in the year of employment in the project or within 7 years before 1 January of the year of employment in the project. This period may be extended by the time spent during that period on long‑term (over 90 days) documented sick leave or rehabilitation benefits related to incapacity for work.
  
  Additionally, this period may be extended by the number of months spent on child‑care and child‑rearing leave granted under the rules specified in the Labour Code, and in the case of women—by 18 months for each child born or adopted, if this method of indicating breaks in a scientific career is more advantageous.
• Motivation and background knowledge in protein quality control and neurodegenerative diseases will be considered a strong advantage.
• Hands‑on experience in mammalian cell culture, preferably including stem cells (e.g., iPSCs) or primary cells.
• Practical experience with biochemical and molecular biology techniques.
• Strong organizational skills and the ability to maintain accurate and well‑documented experimental records.
• Ability to work both independently and collaboratively within a multidisciplinary research team.
• Good communication skills and proficiency in written and spoken English.

• Technical competence, experience and fit of the expertise to the position.
• Soft skills – command of English language, motivation…