Director, Commercial Forecasting

This position may be performed remotely, but requires flexibility and a willingness to travel as needed.

At Praxis, forecasting is a strategic capability that drives critical business decisions and helps accelerate the delivery of life‑changing medicines to patients. The Director of Forecasting will lead all commercial forecasting activities across the portfolio, partnering closely with Finance, Manufacturing, Legal, Commercial, and Executive Leadership to provide clear, data‑driven insights that inform strategy, resource allocation, and long‑term planning.

• Develop, maintain, and continuously improve demand and revenue forecasts across the Praxis portfolio, including pipeline and launch products.
• Lead cross‑functional alignment on forecast inputs and assumptions across commercial, finance, manufacturing, and legal teams.
• Develop analyses and sensitivity models to quantify risks and opportunities across a portfolio of near‑term launches, supporting go‑to‑market and investment decisions.
• Integrate various data sources to track early launch performance, identify trends and variances against forecast, and deliver clear actionable insights to senior and executive leadership.
• Serve as the primary forecasting resource across the organization, managing multiple concurrent forecast cycles, deliverables, and ad‑hoc requests in a fast‑paced launch environment.
• Identify opportunities to improve forecasting accuracy and insight generation through advanced analytics, automation or emerging tools.

• 10+ years of experience in pharmaceutical, biotechnology, healthcare, or life sciences forecasting, commercial analytics, strategic planning, or related disciplines.
• Advanced quantitative and analytical expertise, including patient‑based forecasting, scenario planning, and market modeling, with a proven track record supporting specialty, rare disease, or other complex therapeutic areas.
• Demonstrated success leading forecasting activities for one or more pharmaceutical product launches, including pre‑launch planning, launch readiness, and post‑launch performance assessment.
• Deep understanding of pharmaceutical commercialization, market access, patient flow dynamics, epidemiology, and healthcare data sources.
• Proven ability to build trusted partnerships and shape strategic decisions by turning complex data into clear, actionable insights that drive business impact across all levels of the organization.
• Thrives in ambiguity, adapts quickly to new information while maintaining focus, momentum, and accountability for delivering results.
• Bachelor’s degree in Business, Economics, Finance, Statistics, Data Science, Life Sciences, or a related field required; MBA or advanced degree preferred.

The role requires regular use of a computer, devices or other office equipment, clear communication, and occasional movement. Reasonable accommodations may be made to enable individuals with disabilities to perform these functions.

• 99% of premiums paid for medical, dental, and vision plans.
• Company‑paid life insurance, AD&D, disability benefits.
• Voluntary plans to personalize coverage.
• 401(k) match dollar‑for‑dollar up to 6% of eligible contributions.
• Long‑term stock incentives and ESPP.
• Discretionary quarterly bonus.
• Extremely flexible wellness benefit.
• Generous PTO, paid holidays, and company‑wide shutdowns.

$215,000 - $235,000 USD

Praxis Precision Medicines is an equal‑opportunity employer. We are committed to providing opportunities to all qualified applicants without regard to race, religious creed, color, gender identity or expression, age, national origin, sexual orientation, disability, genetics, military service and veteran status, or any other characteristic protected by federal, state, or local laws.