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Sr. Scientist - Mass Spec Production; LC-MS​/MS

Job in Kansas City, Wyandotte County, Kansas, 66115, USA
Listing for: Kcas, Llc
Full Time position
Listed on 2026-08-31
Job specializations:
  • Research/Development
    Research Scientist, Medical Technologist & Lab Technician, Biotech Research, Pharmaceutical Science/ Research
Salary/Wage Range or Industry Benchmark: 110000 - 160000 USD Yearly USD 110000.00 160000.00 YEAR
Job Description & How to Apply Below
Position: Sr. Scientist - Mass Spec Production (LC-MS/MS)

Commitment:

Regular
- Full Time

Department:

Mass Spectrometry Bioanalysis

Location:

Kansas City - US

Team:

KC
- Mass Spectrometry Bioanalysis
- Prod

Performing critical work that impacts our industry and our world’s health while problem solving and innovating in the field - that is what Sr. Scientists at KCAS Bio get to do every day. If that gets you excited too, then maybe working as a Sr. Scientist at KCAS Bio is the role for you.

When you work as a Sr. Scientist in the Mass Spec Bioanalysis Production group at KCAS, you get to further our mission by leveraging your knowledge in bioanalytical and scientific principles to be responsible for carrying out all aspects of regulated studies, from study setup through reporting. You will also utilize your strong base in scientific principles and regulatory expectations to ensure data integrity, troubleshoot issues, and deliver high-quality results in a GLP-compliant environment.

Our Mass Spec Bioanalysis Development team uses LC-MS/MS (Liquid Chromatography
- Tandem Mass Spectrometry) techniques and sophisticated sample preparation methods to meet bioanalytical needs for drug discovery, preclinical, and clinical studies, including the bioanalysis of drugs and metabolites, biomarkers, and active endogenous compounds in biological fluids and tissues.

When you work as a Sr. Scientist in the Mass Spec Bioanalysis Production group at KCAS, you get to further our mission by leveraging your knowledge in bioanalytical and scientific principles to be responsible for carrying out all aspects of regulated studies, from study setup through reporting. You will also utilize your strong base in scientific principles and regulatory expectations to ensure data integrity, troubleshoot issues, and deliver high-quality results in a GLP-compliant environment.

Our Mass Spec Bioanalysis Development team uses LC-MS/MS (Liquid Chromatography
- Tandem Mass Spectrometry) techniques and sophisticated sample preparation methods to meet bioanalytical needs for drug discovery, preclinical, and clinical studies, including the bioanalysis of drugs and metabolites, biomarkers, and active endogenous compounds in biological fluids and tissues.

In this role, we will rely on you to:
  • Execute and oversee all phases of assigned studies including sample preparation, LC-MS/MS analysis, data review, and report generation in a regulated environment
  • Act as lead scientist on studies, providing work direction, technical guidance, and training to junior scientific staff
  • Be responsible for all client communication related to study conduct and data delivery
  • Interact with QAU to resolve audit findings, deviations, and compliance-related issues
  • Have final authority for sample identification, including resolution of discrepancies with clinical sites and/or clients
  • Be accountable for study timelines, deliverables, and communication of status to management and clients
  • Ensure compliance of all study activities with study protocols, SOPs & GLP regulatory requirements
  • Review and ensure accuracy, completeness, and integrity of data prior to reporting
  • Support audit readiness and participate in client and regulatory inspections as needed
  • Act as a technical resource for troubleshooting assay performance and operational challenges within a production environment
  • Perform all aspects of the job in a way that supports company brand and supports company mission, vision, and values
To qualify specifically for this role, you will have:
  • Bachelor’s, Master’s, or PhD in Chemistry, Biochemistry, or related field with at least 5 years of experience in a bioanalytical laboratory environment
  • Extensive hands-on experience working in a GLP-regulated laboratory environment (required)
  • Strong experience with bioanalytical sample preparation and quantitative LC-MS/MS workflows
  • Experience executing regulated studies, including data review, reporting, and audit support
  • Demonstrated ability to troubleshoot technical and operational issues in a production environment
  • Experience interacting with Quality Assurance and supporting audits and inspections
  • Prior experience acting as a study lead or Principal Investigator-type role preferred

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