Associate Scientist

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Regular Full-Time Kansas City, KS, US

4 days ago Requisition

BioIVT is a leading global provider of research models and value-added research services for drug discovery and development. We specialize in control and disease-state biospecimens, including human and animal tissues, cell products, blood and other biofluids. Our unmatched portfolio of clinical specimens directly supports precision medicine research, aiming to improve patient outcomes by coupling comprehensive clinical data with donor samples. As the premier supplier of hepatic products, including hepatocytes and subcellular fractions, BioIVT enables scientists to better understand the pharmacokinetics and drug metabolism of newly discovered compounds and their effects on disease processes.

By combining our technical expertise, exceptional customer service and unparalleled access to biological specimens, BioIVT serves the research community as a trusted partner in elevating science.

Summary

Under general guidance the Associate Scientist I will perform manufacturing of products, troubleshoot product issues. Conducts routine functions and duties related to the production and/or characterization of products, as well as laboratory upkeep and drug metabolism-related biomedical research.

Duties and Responsibilities

· Prepares subcellular fractions from both human and animal tissues, including necropsy procedures, tissue processing and centrifugation. Dilutes and verifies protein concentration of bulk subcellular fractions.

· Prepares fresh and/or cryopreserved hepatocytes from both human and animal livers, including necropsy procedures, tissue processing, isolation and plating of cells, maintenance of cultured cells, and cryopreservation of cells.

· Manufacture products to meet internal specifications through strict adherence to SOPs. Escalate and assist in making changes to SOP’s or work-flow processes.

· Administers DEA approved Controlled Substances to humanely euthanize purpose bred laboratory animals. Performs small animal surgery, including organ harvesting.

· Performs rodent hepatocyte isolations as a perfusionist. Can isolate rodent hepatocytes from at least 3 mice at a time, with minimal loss of cells.

· Independently process intact human livers and tissues and performs all other types of animal hepatocyte isolations from intact animal livers.

· Maintains laboratories and equipment, performs minor repairs and troubleshooting on equipment. Maintains laboratory supplies and solutions needed for production.

· Completes Batch Record folders, maintains instruments, and equipment logbooks. Executes production related work orders.

Requirements

· Bachelor’s degree (B.S./B.A.) from four-year college or university with 2 years’ experience; combination of education and experience. Bachelor’s degree in a biological or chemical science field preferred.

· Literate and proficient in the use of personal computers and peripheral equipment. Proficient in software programs such as word processing, spreadsheet, and graphics. Ability to learn new software programs.

· Ability to work in a team laboratory environment with knowledge or familiarity with scientific terminology.

· Utilizes sterile technique. Safe handling of dry ice and liquid nitrogen.

· A full-time Monday through Friday workweek with general business hours. This position serves on the On-Call Team and will work rotating weekends and occasionally work evening hours.

We offer a comprehensive benefit package for eligible team members, including medical, dental, vision, short-term/long-term disability, life insurance,…