Executive Assistant, supporting Chief Financial Officer

Olema Oncology is a clinical-stage biopharmaceutical company committed to transforming the standard of care and improving outcomes for patients living with breast cancer and beyond. It’s an exciting time to be part of Team Olema , with our transfor mation into a fully integrated oncology company well underway , t op-line data from our lead program expected later this year , and our first potential commercial launch on the horizon.

Our lead product candidate,palazestrant, isa novel, orallyavailablecomplete estrogen receptor antagonist (CERAN) and selective estrogen receptor degrader (SERD) currently intwopivotal

Phase 3clinicaltrials.

We expect top-line data from OPERA-01,our ongoing

Phase 3 trial ofpalazestrantas a monotherapy in patients with second- or third-lineER+/HER2-metastatic breast cancer (MBC), in the fallwhich, if successful, could lead to our first potential approval and commercial launchin 2027. OPERA-02,our Phase 3 trial ofpalazestrantin combination withribociblibin patients with frontlineER+/HER2- MBC, is enrolling patients.

Togetherwith its mechanism of action, pharmacokinetic properties,andthe potential todemonstrateactivity in bothESR1wild-type and mutant tumors,palazestranthas the potential to transform the metastatic breast cancer treatment paradigm andaccessa $15 billion global market opportunity.

Our follow-on product candidate, OP-3136, is a potent KAT6 inhibitor withthepotential to generate further value and meaningfullyimpactthemetastatic breastcancertreatment landscape – particularly in combination withpalazestrant.

We recently reported encouraging

Phase 1monotherapydata from this program across multiple solid tumor types andareadvancingpatientenrollment in theongoingcombinationarmsin MBC.

Aspiring to transform the metastatic treatment paradigm is an ambitious endeavor that requires aresolute approach to developing better therapies and apassionateteamdedicated tohelping the patients we serve feel better,longer.

Wepossessadeepcommitment toour shared purpose,the sustained pursuit of excellence, cultivatingthecouragerequiredto advance our programs, drive to succeed, and a collective capacity for adaptability through learning, growth, and evolution. Team Olema is made up of nimble self-starters who bring consistency in their quest for the extraordinary every single day.

Ifyou’rereadyto bepartof atenacious,courageous,agile, andgrowingteam,join us in makinga profound impact,together–
for our patients, for your career, and for what’s beyond

About the Role >>>
Executive Assistant, supporting Chief Financial Officer

We are seeking a highly motivated, resourceful, and experienced Executive Assistant to support our Chief Financial Officer (CFO) and approximately 4–6 senior leaders within the organization. This is a highly visible role that requires exceptional organizational skills, sound judgment, discretion, communication excellence, and the ability to effectively manage multiple priorities in a fast-paced, collaborative environment.

The Executive Assistant will provide seamless administrative support across the CFO leadership team, balancing the needs of multiple executives while helping ensure day-to-day operations run smoothly. You will manage communications and coordinate activities with internal and key external parties, including investors and board members. You will be a trusted partner to the CFO and leadership team, as well as a valued member of the broader Executive Assistant team, collaborating with colleagues to provide outstanding support across the organization.

If you are organized, proactive, collaborative, and energized by supporting executives in a dynamic environment, particularly within the biotechnology or pharmaceutical industry this is a unique opportunity to contribute to our mission to develop innovative medicines for breast cancer and beyond.

This role is based in our San Francisco, CA office and requires an on-site presence four days per week.

Your work will primarily encompass:

Executive Support

• Provide day-to-day administrative support to the Chief Financial Officer (CFO) and approximately 4–6 senior leaders .
• Manage complex calendars for multiple executives, balancing…