Executive Director, CMC Regulatory Science

The Role

The individual in this position will be based at the Norwood MA site and will be responsible for managing a team of CMC experts that prepare and oversee CMC and Quality related agency correspondence and regulatory applications. This position will be required to oversee the product strategy for all the products in their portfolio and lead and support all regulatory activities to provide high quality CMC sections of regulatory documentation.

Additionally, interfacing with the leadership in our departments and assuring clear communication of regulatory topics is critical. Reg CMC strategy development to align with the needs of the company, the regulators and the patients will be a key component.

• Lead a team to develop/implement effective CMC regulatory strategies for submissions (e.g. IND/CTA/BLA/MAA) and identify regulatory risks
• Provide expertise for regulatory CMC aspects of product development projects
• Review documents for submission-readiness, to ensure that all submissions conform to health authority guidelines and meet the needs of the company
• Lead Regulatory CMC discussions and interactions with health authorities to facilitate review and approval of submissions at the expert level
• Develop regulatory processes and procedures to support CMC components of regulatory submissions
• Support the creation and maintenance of CMC submission templates
• Provides CMC regulatory expertise to manufacturing and quality teams; evaluates CMC change controls
• Provides interpretation of domestic and international regulatory guidance documents, regulations and directives – advises Manufacturing, Quality and Process/Analytical Development groups regarding their applicability and impact on internal programs. Be a site expert.
• Lead oversight of multiple programs in various therapeutic areas (vaccines, oncology and/or rare diseases) and drive Reg CMC strategy successfully

• MS/PhD degree in a scientific/engineering discipline
• 10+ years of experience in the pharmaceutical/biotech industry
• 8+ years of experience in Regulatory CMC, including DMF/ASMF submissions
• Strong knowledge of current US, EU, and ROW regulations
• Strong experience with CTD format and content regulatory filings
• Exceptional written and oral communication

• MS/PhD degree in Molecular Biology, Pharmaceutics, Chemistry, or closely related field is desirable
• 10+ years of experience in the pharmaceutical/biotech industry, manufacturing and/or analytical focus
• 8+ years of experience in Biologics focused Regulatory CMC

The salary range for this role is $ - $.

Best-in-class healthcare coverage, plus voluntary benefit programs to support your unique needs.

A holistic approach to well‑being, with access to fitness, mindfulness, and mental health support.

Family planning benefits, including fertility, adoption, and surrogacy support.

Generous paid time off, including vacation, volunteer days, sabbatical, global recharge days, and a discretionary year‑end shutdown.

Savings and investment opportunities to help you plan for the future.

Location-specific perks and extras.

Moderna is committed to equal employment opportunity and non‑discrimination for all employees and qualified applicants without regard to a person’s race, color, sex, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, military or protected veteran status, genetic information, sexual orientation, marital or familial status, or any other personal characteristic protected under applicable law. Moderna is a place where everyone can grow.

If you meet the Basic Qualifications for the role and you would be excited to contribute to our mission every day, please apply!

Moderna is an E‑Verify Employer in the United States. We consider qualified applicants regardless of criminal histories, consistent with legal requirements.

We’re focused on attracting, retaining, developing, and advancing our employees. By cultivating a workplace that values diverse experiences, backgrounds, and ideas, we…