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Sr. Principal Engineer - Automation Engineering – Molecule, Lilly Medicine Foundry

Job in Lebanon, Marion County, Kentucky, 40033, USA
Listing for: Biopharma Careers
Full Time position
Listed on 2026-09-14
Job specializations:
  • Engineering
    Automation & Mechatronics Engineer, Systems Engineer, Process Engineer
Salary/Wage Range or Industry Benchmark: 67500 - 173800 USD Yearly USD 67500.00 173800.00 YEAR
Job Description & How to Apply Below

Organization and Position Overview

Lilly recently announced a $4.5 billion investment to create the Lilly Medicine Foundry, a new center for advanced manufacturing and drug development. The first-ever facility of its kind, combining research and manufacturing in a single location, the Medicine Foundry will allow Lilly to further develop innovative solutions to optimize manufacturing processes and increase capacity for clinical trial medicines, while also reducing costs and environmental impact.

The Sr. Principal Engineer - Automation Engineering will work as a member of the Automation Engineering Department at Eli Lilly, Foundry. The Sr. Principal engineer will provide automation support for one or more operating areas across site and/or for capital projects. Process Automation is core to delivering a right first time facility start up and continued support of ongoing manufacturing operations into the future.

The Sr. Principal Engineer is also responsible for the productivity and mentorship of the employees with the purpose of ensuring that reliable and complaint-controlled applications and systems are used in the manufacturing itionally, the Sr. Principal Engineer, as a key technical expert partners to influence and implement within the process control organization and across functional disciplines to support the process control technical agenda, business plan priorities, and compliance objectives.

In the project delivery phase and startup phase of the project (startup expected 2025 to 2028), automation engineering roles will be fluid and dynamic as we endeavor to support the project delivery, build a new organization, develop and implement the necessary systems and business processes required to support GMP operations, and build the site culture. This will require significant collaboration, creativity and resilience as the site grows to a full scale GMP manufacturing through start up.

Responsibilities

Key Objectives/Deliverables:

Technical Leadership

Mentor process control team, including design, controls philosophy, implementation and commissioning

Process control work implementation and coordination

Review and monitor financial performance; commit to meeting targets

Develop and implement the Automation Engineering Project Plan.

Operational Excellence

Technically lead and oversee the work of Site Area leads and System Integrator including Functional Requirements, Design Specifications, DCS Application Software, Test Specifications.

Lead/Participate in design reviews and DeltaV application software reviews, attend equipment and software FATs

Lead a team of automation engineers supporting commissioning

Provide periodic status updates to Project Management

Devise functional requirements and process control strategies for control systems in collaboration with Process Engineering

DCS and SCADA software design, coding/configuration and testing (sequence logic, graphics, batch software etc.)

Perform automation engineering activities including design, tuning and troubleshooting of control loops

Implement and support electronic systems (such as plant historians, applications and software integration) used to capture process automation related production data

Maintain the validated state of the site control systems in line with Lilly quality standards including the development and execution of validation strategies and associated documentation

Automation support for capital projects including new product introductions

Promoting the use of automation to improve productivity, operational efficiency and compliance

Developing a ‘network’ of corporate contacts and leveraging corporate expertise when needed

Organizational Capability

In coordination with automation and compliance consultants, set and reinforce standards…

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