Research Technician II - Gastroenterology; Hepatology

Location SAINT LOUIS, MO 63110 Scheduled Hours 40

The Schwartz Laboratory in the Division of Gastroenterology, Department of Medicine, at WashU Medicine in St. Louis is seeking motivated and creative scientists to join our interdisciplinary research program investigating the biology of hepatitis B virus (HBV) and the mechanisms that allow the virus to establish and maintain chronic infection. Our long-term goal is to understand the complex interactions between HBV and its host that drive viral persistence and to use these insights to identify new strategies toward a functional cure for chronic hepatitis B, which remains a major global health challenge and an important cause of liver related morbidity and mortality.

Our laboratory has a strong history of developing innovative human models of viral infection. We were among the first groups to establish hepatitis B and hepatitis C virus infection models using stem cell-derived hepatocytes, and we have continued to combine these systems with primary human hepatocytes, CRISPR/Cas9 gene editing, and genetically distinct HBV clones to dissect the host and viral factors that determine infection and persistence.

Recent work from the laboratory, published in Cell, identified a nucleosome-level molecular switch that primes and influences HBV infection (10.1016/j.cell.. Assists with the technical aspects of studies and experiments, including documentation and preparation of materials.

• Assists with research studies, experiments and assays, including collection of data, preparation of solutions and setup and maintenance of equipment.
• Performs data entry and maintains data files on research.
• Prepares tissue cultures, reagents, probe tests, etc.
• Complies with established safety procedures and maintains required documentation on laboratory and specimen conditions.
• Ensures lab conditions and equipment are properly cleaned and maintained in accordance with established procedures.
• Assists with general lab maintenance and cleaning.
• Performs other duties as assigned.

This position works in a laboratory environment with potential exposure to biological and chemical hazards. The individual must be physically able to wear protective equipment and to provide standard care to research animals. The above statements are intended to describe the general nature and level of work performed by people assigned to this classification. They are not intended to be construed as an exhaustive list of all job duties performed by the personnel so classified.

Management reserves the right to revise or amend duties at any time.

• Education:
  
  Bachelor’s degree or combination of education and/or experience may substitute for minimum education.
• Certifications/Professional Licenses:
  No specific certification/professional license is required for this position.
• Work Experience:
  
  No specific work experience is required for this position.
• Skills:
  
  Not Applicable
• Driver's License: A driver's license is not required for this position.

The ideal candidate will have up to one year of experience in a laboratory setting.

• Education:
  
  No additional education unless stated elsewhere in the job posting.
• Certifications/Professional Licenses:
  No additional certification/professional licenses unless stated elsewhere in the job posting.
• Work Experience:
  
  No additional work experience unless stated elsewhere in the job posting.
• Skills:
  
  Communication, Detailed Reports, Laboratory Instrumentation, Laboratory Research, Software Program, Working Independently

Grade R06-H Salary Range $16.92 - $26.44 / Hourly The salary range reflects base salaries paid for positions in a given job grade across the University.…