Medicinal Organic Chemist - Chemical Biology (BS or MS

Medicinal Organic Chemist - Chemical Biology (BS or MS)

Job -

Aug 13, 2026

USA

The Discovery Sciences team is seeking a Research Scientist to work as an organic medicinal chemist at Novartis’ Biomedical Research headquarters in Cambridge, MA, USA.

Internal job title: Research Scientist I / Research Scientist II

Position Location
:
Cambridge, MA, onsite. #LI-onsite

In this lab-based role, with team assistance, you will carry out multi-step organic chemistry synthesis routes preparing organic molecules that test molecular biology hypotheses and interrogate molecular pathways implicated in disease. You will leverage your expertise in mechanistic organic chemistry to effect functional group transformations building up complex structures. You will use modern purification techniques for final product isolation and then gather and analyze characterization data for structural confirmation.

You will analyze assay results using data tools and leveraging Data Science and A.I. to work through the Design, Make, Test, Analyze (DMTA) cycle.

Key responsibilities:

• Designcompoundsbased off team or individual hypotheses,andcarry out multi-step syntheses of small molecules
• Analyze and interpret data,solve synthetic issues and design follow-up experiments
• Collaborate with peers and workeffectivelyand efficientlyasan important part of across-functional team
• Adhere to laboratorysafetypolicies and practices
• BS orMS degreein chemistry; 0-5 years of industrial experience. This is not a PhD-level position.
• A mechanistic understanding of organic chemistry; knowledge of modern organic synthetic methods; medicinal chemistry knowledge is a plus
• Familiarity with common chemistry synthesis, purification, and analytical techniques
• Strong problem solving and communication skills
• Expertise in chemical biology and synthesis of chemical probestoaddress impactful biological and conceptual questions.
• Hands-onexperienceinsynthesisof a wide range of compound classes, practical techniques,method development,and purification techniques.

Compensation and Benefits:

The salary for this position is expected to range between $66,800 and $124,000 per year for Research Scientist I, and between $81,200 and $150,800 per year for Research Scientist II. The final salary offered is determined based upon factors like, but not limited to, relevant skills and experience, and upon joining Novartis will be reviewed periodically. Novartis may change the published salary range based on company and market factors.

Your compensation will include a performance-based cash incentive and, depending on the level of therole, eligibility to be considered for annual equity awards.

US-based eligible employees will receive a comprehensive benefits package that includes health, life and disability benefits, a 401(k) with company contribution and match, and a variety of other benefits. In addition, employees are eligible for a generous time off package including vacation, personal days,holidays and other leaves.

Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together?

The Novartis Group of Companies are Equal Opportunity Employers. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, sex, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status.

Accessibility & Reasonable Accommodations

The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or to perform the essential functions of a position, please send an e-mail to [email protected] or call  and let us know the nature of your request and your contact information.

Please include the job requisition number in your message.

Division Biomedical Research

Business Unit Research

Location USA

State Massachusetts

Site Cambridge (USA)

Company / Legal Entity U175 (FCRS = US175) Novartis Institutes for Bio Medical Research, Inc.