Senior Associate Scientist​/Scientist I, Protein Sciences

Location: Redwood City, CA

Immun Edgeis a biopharmaceutical company committed to developing novel therapeutics for patients with serious or life-threatening diseases. With a highly experienced team of experts in immunology and drug development, we are pioneering innovative approaches to target and modulate key molecular pathways that regulate the immune response. At Immun Edge , we are driven by a shared commitment to improving human health through innovative science.

We are building a culture based on kindness, collaboration, and a deep passion for advancing science. As an early joiner to the company, you will help cultivate an environment where every team member is encouraged to challenge ideas, think critically, and contribute their unique perspectives. We value openness, transparency, and continuous learning, and want to empower our employees to take ownership of their work while fostering a sense of community and teamwork.

Whether you’reworking in the lab, the office, or across functional teams, you will find an inclusive space where your contributions matterand your professional growthissupported.

Join us in shaping the future of biotechnology. Together, we can change lives.

We’re looking for a hands-on and passionate Senior Research Associate/Scientist Ito join the protein purification and analytics team in the Biotherapeutics Department. This role is ideal for a scientist who enjoys hands-on laboratory work and wants to directly influence the discovery and development of next-generation biologics. As part of the protein purification and characterization team, you’ll contribute to the production and characterization of therapeutic proteins and antibodies, with an emphasis on complex biologics such as bispecific and multi-specific antibodies, as well as challenging antigens.

You will own purification and analytical work streams from initial material assessment through the delivery of high-quality protein and will collaborate with protein engineering, discovery biology, and cross-functional project teams to troubleshoot molecule-specific challenges and inform candidate design and selection. This position may be filled at the Senior Associate Scientist or Scientist I level based on relevant experience, technical depth, and demonstrated independence.

• Execute purification workflows for mono-clonal and bispecific/multi-specific antibodies, and other therapeutic proteins, using appropriate chromatographic techniques, including affinity, IEX, HIC, SEC, and mixed modes.
• Characterize the quality of biomass and partially purified materials; analyze purity impurity distribution, aggregation, charge heterogeneity, determine expression titter, molecule identity, protein assembly quality, PTMs, and other quality attributes; develop and transfer methods at analytical scale and process scale.
• Optimize purification process for small-scale and large-scale productions to support discovery, lead optimization, and preclinical studies.
• Optimize formulation process for high concentration formulation and maintain ultra-low level or low level of endotoxin across purification and formulation instruments and devices.
• Troubleshoot production, purification, and quality challenges; identify root causes and improve process to enhance yield, purity and overall protein quality;
  Partner with the protein-engineering team to recommend molecule redesign and engineering solutions when production problems are tied to intrinsic sequence liabilities.
• Maintain detailed documentation of experiments, including materials, protocols, results, and conclusions, in electronic lab notebooks and technical reports. Maintain good records of protein inventory.
• Present data, conclusions, and…