Research Associate – In Vivo Electrophysiology & Behavior

The Allen Institute accelerates science for a healthier world through large-scale research designed to answer some of the most complex questions in biology. Our multi-disciplinary teams generate foundational knowledge, tools, and data to understand how our brain, cells, and immune system work. We share our work openly so others can build on it, move faster, and ask bigger questions. We drive discovery forward and create new possibilities for improving human health.

The goal of the Neural Dynamics accelerator is to understand how the brain generates flexible behavior. We aim to uncover the algorithms—implemented by dynamics in brain-wide neural circuits—that allow animals to build internal models, process information, and choose actions.

We are seeking a Research Associate to contribute to a set of projects to record the activity of thousands of neurons distributed across many brain regions in parallel. The ideal candidate will be team-oriented, have knowledge in neuroscience and behavior, and display a strong interest in studying brain-wide circuits during behavior. This position will leverage state-of-the-art electrophysiological methods, such as Neuropixels probes, as well as molecular and transgenic resources.

The goal is to record simultaneously from many anatomically connected regions while mice are engaged in a variety of cognitive tasks. The Research Associate will work alongside a diverse team of Scientists, Technicians, Engineers, and Investigators, and so collaboration and communication skills are key.

At the Allen Institute, we believe that science is for everyone – and should be open to everyone. We are dedicated to combating biases and reducing barriers to STEM careers more broadly.

We also believe that science is better when it includes different perspectives and voices. We strive to make the Allen Institute a place where everyone feels like they belong and are empowered to do their best work in a supportive environment.

We are an equal-opportunity employer and strongly encourage people from all backgrounds to apply for our open positions.

Essential Functions

• Collect in vivo electrophysiological, optogenetics, and/or optical physiological data from mouse cortex using cutting-edge recording systems
• Train mice to perform various foraging behavioral tasks
• Participate in lab maintenance and weekly tasks
• Carry out analyses to assess overall data quality and use this information to update and refine experimental protocols
• Use histological techniques to identify probe recording location

* Note:

Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions. This description reflects management’s assignment of essential functions; it does not proscribe or restrict the tasks that may be assigned.

Required Education and Experience

• Bachelor’s degree in neuroscience or a related field

Preferred Education and Experience

• 2 years of experience in a research lab
• Experience working with mice greatly preferred
• Practical experience in in vivo electrophysiology and/or mouse behavior
• Strong scientific communication skills (written and oral)
• Ability to work in a team-based environment
• Experience with rodent surgeries
• Laboratory environment - possible chemical, biological, or other hazardous substances exposure Possible exposure to Bio Safety Level 2 organisms, such as recombinant viruses This may include wearing personnel protective equipment (PPE)

Animal Care Services

• Exposure to and handling of laboratory animals required
• Pre and post-operative care for mice
• Administration of compounds to mice (iv, ip, sc, po, im, ro, icv)
• Perform health assessments of mice
• Perform euthanasia and tissue collections

Physical Demands

• Fine motor movements in fingers/hands to operate…