PK​/PD Principal Scientist

Zoetis, a global leader in animal health, seeks an enthusiastic colleague to join our Veterinary Medicine Research and Development (VMRD) PK/PD Scientist Team to discover and develop novel therapeutics for veterinary medicine.

• Independently design and analyze in vivo PK/PD, PK and TK studies in multiple veterinary species, including writing study protocols and reports.
• Provide PK and PK/PD modeling and simulation to help select lead candidates and optimize dose regimens.
• Collaborate with the bioanalytical team to assess suitability of analytical assays and forecast analytical requirements for projects.
• Lead development of scientific strategy across therapeutic areas with a focus on mechanistic platforms/biomarkers to aid in translation, measurement of target engagement, and dose regimen predictions.
• Work collaboratively and communicate effectively with multidisciplinary teams to design and prosecute studies in line with the strategic direction of the project.
• Present research results to scientific teams, management, and regulatory agencies.
• Write sections of regulatory submissions, respond to inquiries from regulatory agencies, and maintain knowledge of regulatory guidance documents.

• Ph.D. in pharmacology, biochemistry, or a related field with 4 or more years of relevant pharmaceutical development experience.
• DVM DACVCP or DVM Dipl. ECVPT (highly desirable).
• Proven ability to design, analyze, and interpret in vivo PK and PK/PD studies.
• Experience with biotherapeutics (protein therapeutics) (highly desirable).
• Skilled in the use of PK and PK/PD analysis software such as Win Nonlin, Monolix, or Watson.
• Excellent verbal and written communication skills.
• Self‑starter, able to prioritize work and work efficiently with minimal supervision.
• Working knowledge of bioanalytical methodology.
• Knowledge of ADA assays and assessment of immunogenicity of biotherapeutics (highly desirable).
• Experience in PK/PD modeling and simulation such as PBPK, QSP, or population PK modeling using NONMEM, R, or related software (highly desirable).
• Experience interacting with regulatory agencies (highly desirable).
• Experience conducting GLP studies (desirable).

The US base salary range for this full‑time position is $114,000 - $185,000. The position is also eligible for short‑term incentive compensation, long‑term incentives, and a comprehensive benefits package that includes healthcare and insurance benefits, a 401(k) plan with a match and profit‑sharing contribution, and 4 weeks of vacation.

Zoetis is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability, veteran status, or any other protected classification.

Disabled individuals are given an equal opportunity to use our online application system. Zoetis offers reasonable accommodations as an alternative if requested by an individual with a disability.