P2621 Senior) Pharmacometrician

AtDebiopharmyou will be at the forefront of the fight against cancerand infectious diseases, and you will have the opportunity to work on new innovative medicines for patients. Efficacy is our mode of action, saving lives our collective target.

In this role, you will contribute tothe modeling and simulationactivitiesfor projects in Oncology and Antibiotics, leveraging state-of-the-artPK,PK/PDand othermethodologies. You will conduct pharmacometricsanalysesto add value, support, and accelerate the development of Debiopharm'sinnovative medicine.

• Performing (hands-on) and/or monitoring (oversight) pharmacometrics(PMx) activities from non-clinical to clinical drug development stages of primarily oncologyprograms.
• Conductrelevantmodeling and simulation activities in compliance with regulatory guidelines and internal SOP, including but not limited to:
  
  POPPK, PK/PD, ER, disease progression modeling,trial simulation,model-based optimal trial design,documentation..
• Contribute to developing,implementing and promotinginnovativePMxmethodologies.
• Contributetodevelopingandexecutingthemodel-informed drug developmentstrategiesfromearly tolatedevelopmentstages
• Communicating onPMxresultsin a cross-functional environment.
• Contribute to the preparation ofPMxdocumentation to support regulatory or other cross-functional activities; may participate in interactions with Health Authorities.
• Contribute to external scientific communications (publications, posters and oral presentations, and press releases). Participate in external scientificforums, conferences and courses to stay updated with latest industry trends and establish professional networks.
• Supports the In& Out licensing activities as part of Debiopharm'smodel.

• PhD or equivalent degree in Pharmacometrics, mathematics, statistics, or similar disciplines with demonstrated expertise in pharmacometrics(e.g.,population PK and PK/PD modeling, exposure-response analysis, disease progression models,clinical trial simulation)
• At least 3-5yearsrelevant experience inPMxwithin industry or academia; experience in oncology is an asset
• Solidhands-on experience in Population PK/PD modellingsoftware(Monolix,NONMEM);
  
  Excellent programming skills (R,Python,...)
  Knowledge Knowledge of PBPK modeling software(e.g.:SimCYP, PK-Sim, Gastro-Plus) is an asset.
• In depth understanding ofpharmacology and pharmacokinetic concepts, as well as knowledge ofpreclinicalandclinical development
• Knowledge of GCP, GCLPand relevant regulatory guidelines
• Ability to work independently in afast-pacedenvironmentwhilemaintainingstrong collaborationsbothwithinandcrossfunctions.
• Strong organizational skills and ability to handle multiple tasks simultaneously
• Results interpretationcapabilities,strongscientific/technical wring/reportingabilities, andinterpersonalskillsin
  
  English,French is an asset

• International,highly dynamic environment with along-term vision.
• Cross-functional collaborationat the forefront of the most advanced scientific developments in oncology and anti-bacterialindustry
• Exposuretoa wide variety ofareasand functions within clinical development and thepharmaceuticalindustry
• Opportunity of personal development through specifictrainingsandattendancetoscientific conferences
• Participation in a company where innovation, people and entrepreneurship are the fundamentalkeys tosuccess.
• Proud to bean Equal-Pay certified, we ensure offering to all our employees the same opportunities

The use of external staffing agencies or recruiters requires prior approval from our Human Resources Department. The Human Resources Department at Debiopharmrequests external staffing agencies or recruiters not to contact

Debiopharmemployees or members of the Board of Directors directly in an attempt topresent candidates.

Submission of unsolicited resumes in advance of an agreement between the Human Resources Department and the external staffing agency or recruiter does not create any implied obligation on the part of Debiopharm.

Debiopharmwill not accept unsolicited resumes from any source other than candidates themselves for either current or future positions.