Scientist - Computational Biology

Company Description

By working at Harvard University, you join a vibrant community that advances Harvard's world‑changing mission in meaningful ways, inspires innovation and collaboration, and builds skills and expertise. We are dedicated to creating a diverse and welcoming environment where everyone can thrive.

The Wyss Institute’s mission is to transform healthcare and the environment by emulating the way nature builds. We harness the imagination of academia and the focus of industry to translate ground‑breaking technologies into commercial products that solve big problems. We support research that universities, companies, and venture capital firms don’t fund because they view it as too risky. We prefer to use the word “challenging”, and we love challenges.

For more information discover our technologies, catch up on our recent news, or watch our latest videos.

You are a collaborative, impact‑focused problem solver who wants to be part of a dynamic team dedicated to creating and commercializing novel approaches to global challenges in healthcare and sustainability. You want the opportunity to explore your scientific interests and apply your knowledge to tackle ambitious projects in a fast‑paced, entrepreneurial‑minded environment with resources and support from top‑notch scientific, operations, and administrative professionals.

You enjoy working with highly motivated, diverse teams and leveraging your expertise to create innovations that can change the world.

We are looking for a Scientist I to join our Diagnostics Accelerator team with significant expertise in analyzing Next Generation Sequencing (NGS) and other high throughput datasets (mass spectrometry) for biomarker discovery. You will work with a multidisciplinary team on developing multi‑omic technologies for investigating pathological states from human biofluids. You will lead development of novel Next Generation Sequencing (NGS) computational methods that will be used across different diseases.

Although this role is primarily computational, you will also have an opportunity to participate or be trained in experimental methods and ideally serve as a hybrid computational / experimental scientist.

• Perform computational analysis of NGS (RNA‑Seq, etc), mass spectrometry, and other large scale datasets to find novel biomarkers for different diseases
• Help with experiments developing novel platforms for biomarker discovery
• Provide training and guidance to other lab members on experimental technique
• Present data at internal Wyss Meetings and prepare presentations for updating program officers from funding agencies.
• Develop pipelines for selecting biomarkers from large multi‑omic data sets. (NGS, mass spectrometry, etc.)
• Develop new technologies for profiling of biomarkers from human biofluids.
• Demonstrate a commitment to teamwork, scientific rigor, and collaboration within and across teams.

• Bachelor’s degree in biology, computer science, engineering, or a related field and at least 4 years of experience working with NGS data (RNA‑Seq, etc).
• Strong programming skills in Python and/or R, and extensive expertise in writing computational biology workflows required.
• Advanced education may count towards years of experience.

• MS or PhD in computational biology preferred but not required.
• Experience with ML/AI workflows helpful.
• Experience with analyzing mass spectrometry data helpful.
• Prior experimental experience (molecular biology, NGS library preparation, programming liquid handlers/automation) helpful.

• Standard Hours/
  
  Schedule:
  
  35 hours per week
• Visa Sponsorship Information: Harvard University is unable to provide visa sponsorship for this position
• Pre‑Employment Screening: Identity, and Education.

At the Wyss Institute, you’re a member of a supportive, dynamic community that is united by its shared goal of changing the world through groundbreaking technology development and commercialization. We encourage your professional growth and development through mentorship…